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Why do renal patients need increased amounts of folic acid and cobalamin?

Frequently Asked Questions : Diatx®Zn
Recent studies have shown that decreased vitamin levels, especially folic acid, may be associated with increased blood levels of homocysteine. Homocysteine is a risk factor for cardiovascular disease (CVD) and CVD is highly prevalent in patients with End Stage Renal Disease (ESRD). ESRD patients may benefit from aggressive multi risk factor management. Studies also show that renal patients are more responsive to increased doses of folic acid versus lower doses.
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What is folic acid and where can I get it?

Birth Defects Resources: Folic Acid & Spina Bifida Frequentl...
Folic acid is a B-vitamin. The recommended amount to prevent spina bifida and other neural tube defects is 400 micrograms (0.4 milligrams) of synthetic folic acid daily. Convenient ways to make sure that you get enough folic acid: Take a vitamin with 400 mcg of folic acid every day. (Folic acid pills are small and easy to swallow). Both folic acid pills and multivitamins can be bought at grocery stores, pharmacies, or discount stores.
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Spina Bifida Association Houston Gulf Coast
Folic acid, a common water-soluble B vitamin, is essential for the functioning of the human body. During periods of rapid growth, such as pregnancy and fetal development, the body's requirement for this vitamin increases. Folic acid can be found in multivitamins, fortified breakfast cereals, dark green leafy vegetables such as broccoli and spinach, egg yolks, and some fruits and fruit juices. However, the average American diet does not supply the recommended level of folic acid.
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Can women get too much folic acid?

Birth Defects Resources: Folic Acid & Spina Bifida Frequentl...
Folic acid has no known toxic level. If you were to eat a bowl of fully fortified cereal (400 micrograms), take a folic acid supplement (400 mcg), and eat fortified foods and foods rich in folate, women of reproductive age would not have a problem with too much folic acid. Even in very high amounts folic acid is non-toxic. Nevertheless, it is recommended that women consume no more than 1,000 micrograms of synthetic folic acid a day.
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Are women getting enough folic acid?

Birth Defects Resources: Folic Acid & Spina Bifida Frequentl...
Even though there are several ways to get 400 micrograms (0.4 milligrams) of folic acid every day, two thirds of women in the United States do not consume enough folic acid.
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What is the benefit of doubling the amounts of alpha-lipoic acid and folic acid?

Antioxidants AntiAging FAQ Nutrition Minerals Natural Vitami...
Alpha-lipoic acid is a water-soluble and fat-soluble antioxidant that is ready and able to be used wherever your body needs it. By increasing the dosage from 50 mg to 100 mg, alpha-lipoic acid can recharge other antioxidants, doubling their ability to fight against deadly free radicals. Folic acid is an essential vitamin for women because it helps prevent serious birth defects.
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What are other health benefits to taking folic acid?

Birth Defects Resources: Folic Acid & Spina Bifida Frequentl...
High levels of the amino acid homocysteine are independently associated with an increased risk of heart disease and stroke. It has been shown that taking folic acid lowers homocysteine levels in both men and women, but it is not yet known whether folic acid supplementation also lowers the risk of heart disease and stroke. There are some indications that folic acid use may also reduce the risk for other birth defects, such as cleft lip and palate and certain congenital heart defects.
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Warburtons > Contact Us > Frequently Asked Questions
Folic acid is essential for growing cells and for healthy blood. Bread is a natural source of folic acid.
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Ensure - Frequently Asked Questions
This B vitamin is essential for keeping the body healthy. It benefits everything from the brain and nervous system to bone marrow and the intestinal tract. There???s also evidence that folic acid lowers an amino acid in the blood (homocysteine) that has been linked with increased risk for heart disease and Alzheimer???s. If you???re healthy, you need about 400 micrograms a day. Think foliage: Leafy greens are among the richest sources of folic acid.
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What about patients with renal insufficiency?

profaq
In a cross-study comparison, celecoxib AUC was approximately 40% lower in patients with chronic renal insufficiency (GFR 35-60 ml/min) than that seen in subjects with normal renal function. No significant relationship was found between GFR and celecoxib clearance. Patients with severe renal insufficiency have not been studied.
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Can BYETTA be used in patients with renal insufficiency or end-stage renal disease?

Byetta (exenatide) for Type 2 Diabetes Safety
BYETTA is not recommended for use in patients with end-stage renal disease or severe renal impairment (creatinine clearance <30mL/min). In patients with end-stage renal disease receiving dialysis, single doses of BYETTA 5 mcg were not well tolerated due to gastrointestinal side effects. For complete safety profile and other important prescribing considerations, see the full Prescribing Information.
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Should men take folic acid supplements too?

Frequently Asked Questions - DrDonnica.com - The First Name ...
Ganglion cysts are also known as "Bible cysts" because people used to try "treating them" by smashing a large book (like a Bible) on top of them. Do not do this! Do you have any information on Gastroparesis? My wife is suffering through this since she had her thyroid oblated with radioactive iodine 2 months ago. I am a recovered anorexic and I would like to know if there is any way that I can get involved with helping other girls through this struggle.
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Should we offer preconception folic acid?

MCH Frequently Asked Questions
C.D.C.'s primer Diagnosis and Management of Food borne Illnesses. You can also get 3.0 hours of C.M.E
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Ensure - Frequently Asked Questions
This B vitamin is essential for keeping the body healthy. It benefits everything from the brain and nervous system to bone marrow and the intestinal tract. There's also evidence that folic acid lowers an amino acid in the blood (homocysteine) that has been linked with increased risk for heart disease and Alzheimer's. If you're healthy, you need about 400 micrograms a day. Think foliage: Leafy greens are among the richest sources of folic acid.
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Dr.com Reference Library Congenital conditions - Spina Bifid...
Folic acid, a common water-soluble B vitamin, is essential for the functioning of the human body. During periods of rapid growth, such as pregnancy and fetal development, the body's requirement for this vitamin increases. Folic acid can be found in multivitamins, fortified breakfast cereals, dark green leafy vegetables such as broccoli and spinach, egg yolks, and some fruits and fruit juices. However, the average diet does not supply the recommended level of folic acid.
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Article: Pregnancy and Nutrition: NWHIC - CureResearch.com
Pregnancy doubles a woman's need for folate (folic acid or folacin). Folic acid has been shown to be important in preventing neural tube defects, such as spina bifida and anencephaly and is essential to the formation of red blood cells. Severe folate deficiency can result in a condition called megaloblastic anemia, which occurs most often in the last trimester of pregnancy. In this condition, the mother's heart, liver and spleen may become enlarged which and can threaten the life of the fetus.
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Health Testing - Wellness Testing and Folic Acid Health Test...
Folic acid is also known by several other names - pteroyl-L-glutamic acid, Vitamin M, folate, folinic acid, folacin etc. It is a water soluble vitamin B (B9) compound and can be found commonly in leafy green vegetables like kale and spinach, in orange and in enriched grains.
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FAQs, Folic Acid, NCBDDD, CDC
Folic acid is a B vitamin that the body needs to make healthy new cells. If a woman has enough folic acid in her body before and during pregnancy, her baby is less likely to have an NTD. Women need to take folic acid every day, starting before they get pregnant. Every woman who could possibly get pregnant should take 400 micrograms (400 mcg or 0.4 mg) of folic acid daily in a vitamin or in foods that have been enriched with folic acid. Take one vitamin with folic acid each day.
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What treatments/interventions are available for NPS patients when renal impairment is detected?

Frequently Asked Questions
Some physicians may prescribe medications. In more severe cases, dialysis or kidney transplantation may be needed. Research indicates that kidney disease does not reoccur once the patient undergoes kidney transplantation.
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How much folic acid does a woman need to consume everyday?

FAQs for Women, Infants & Children Nutrition Services
All women of childbearing age should take a multivitamin containing 400 mg. of folic acid everyday even if they are not planning a pregnancy. This is because half of all pregnancies are unplanned and folic acid can help prevent the risk of certain birth defects that occur very early on in pregnancy, before most women even know they are pregnant.
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My doctor tells me I need to take a folic acid supplement during my pregnancy. What does it do?

Common Questions (Preconception, Fertility, Pregnancy, Labor...
Folic acid helps promote the production of red blood cells in both your body and your developing baby. Red blood cells are important to minimize the onset of physiological anemia as your pregnancy develops. It also reduces the risk of neural tube defects in the fetus. Most doctors recommend a supplement containing at least 0.4 milligrams of folic acid during your pregnancy. The US Public Health Service suggests you take the supplement if your capable of becoming pregnant.
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Why are activated folic acid and B12 important?

ProThera - Frequently Asked Questions
Folic acid and vitamin B12 help prevent the build-up in the body of homocysteine, a potentially toxic amino acid metabolite that damages arteries and increases the risk of heart disease. The biologically active forms of folic acid, 5-methyltetrahydrofolate (5-MTHF), and vitamin B12, methylcobalamin, are used in CardioThera? instead of common forms of these B-vitamins found in most other supplements.
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Which type of bread has more folic acid?

Warburtons > About Warburtons > General FAQs
Folic acid is naturally present in bread. However, more is found in wholemeal breads. Click here for more information about folic acid.
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How much folic acid should I be taking?

FAQs - Prenatal Nutrition - Enfamil
Health Canada recommends that women take a daily supplement of 0.4 mg of folic acid together with dietary sources of folic acid before conception and during the early weeks of pregnancy to decrease the risk of neural tube defects like spina bifida.
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