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What is the difference between active and latent TB?

Scantibodies Clinical Laboratory - Home Page
Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but TB bacteria can attack any part of the body such as the kidney, spine, and brain. TB is spread through the air from one person to another. A person with active TB is contagious and symptoms may include coughing, unexplained weight loss, night sweats, fever, chills, no appetite and fatigue.
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What is the difference between latent TB and active TB?

Frequently Asked Questions about Tuberculosis (TB)
Latent TB is when the body’s immune system forms a wall around the TB bacteria so the TB bacteria cannot multiply or spread. The TB germs are essentially “asleep” in your body when you have latent TB. A person with latent TB is not contagious (cannot spread TB to other people) and has no symptoms. TB bacteria can stay latent for long periods of time (e.g. from many years to the rest of your life). Active TB is when the body cannot adequately fight the TB bacteria.
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What is the difference between latent TB infection (LTBI) and TB disease?

Public Health | Monroe County, NY
People with latent TB infection test positive on their skin test for TB but they are not sick and they can not spread the disease to anyone else.
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Which people with latent TB are at highest risk of developing active disease?

Screening Tuberculosis
Overall, 5-10 percent of all people with latent tuberculosis will go on to develop active disease. The risk of reactivation is greatest in those with recent TB infection and in people with conditions which weaken the immune system. The following groups are considered to be at high risk: Young children. (Infants have a 40% chance of progressing to active disease, and children are more likely to develop life-threatening forms of TB).
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Who should be screened for latent TB?

Screening Tuberculosis
People who live or work in places where TB is more common, such as homeless shelters, migrant labor camps, prisons, jails, hospitals, and some nursing homes. Patients with HIV, silicosis, malnutrition, renal failure, or other conditions placing them at higher risk for active TB.
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What is latent TB infection?

Tuberculosis (TB) Treatment & Control Clinic - Southern ...
In most people who breathe in TB bacteria and become infected, the body is able to fight the bacteria to stop them from growing. The bacteria become inactive, but they remain alive in the body and can become active later. This is called latent TB infection. Many people who have latent TB infection never develop active TB disease. In these people, the TB bacteria remain inactive for a lifetime without causing disease.
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What is the difference between latent TB infection and TB disease?

ID Associates: Tuberculosis
Latent TB infection results when the TB bacteria live in your body without making you sick. The bacteria lie inactive because the body is able to fight the bacteria to stop them from growing. These people have no symptoms and can’t spread the disease to others. TB disease can result if the bacteria become active when the immune system can’t stop them from growing.
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Where Can I get Treatment For Latent TB Infection or Active TB Disease?

Frequent Questions - Public Health Department (DEP)
If you have a regular health care provider, you should see them first. If you don’t have a health care provider, you can receive TB Treatment from the Santa Clara Valley Health and Hospital System TB Clinic. For more information about the TB Clinic see the Related Link below.
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What is latent TB infection (LTBI)?

Washington County -- Tuberculosis
In most people who breathe in TB bacteria and become infected, the person's body is able to fight the infection and keep them from growing. The TB bacteria become dormant, and this is called latent TB infection. People with latent TB infection: Many people who have latent TB infection never develop active TB disease. In these people, the TB bacteria remain in the body for a lifetime without causing disease.
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What should I do if I have spent time with someone with latent TB infection?

Frequently Asked Questions about Tuberculosis (TB)
A person with latent TB infection cannot spread germs to other people. You do not need to be tested if you have spent time with someone with latent TB infection. However, if you have spent time with someone with active TB disease or someone with symptoms of TB, you should be tested with a skin test.
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Why treat latent TB?

Latent TB: FAQ's
Completing a course of treatment decreases the person's lifetime risk of developing active TB by 90%. Treatment of latent TB is also a cornerstone of efforts to eliminate TB in society, since it minimizes the number of infectious cases.
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Who should be treated for latent TB?

Latent TB: FAQ's
In general, anyone with a positive TB test who is at high risk of reactivation should be treated, regardless of age. (See above list of high-risk groups). Although the 2000 CDC guidelines seem to suggest that foreign-born persons not be treated if they have been living in the United States more than 5 years, a recent study found that 25% of all cases of active TB in the US occur in this population.
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How is latent TB treated?

Latent TB: FAQ's
Nine months of isoniazid (INH) is the preferred treatment regimen for all cases of latent TB, including HIV patients, pregnant women, and children. A minimum of 270 doses must be administered within 12 months. In pregnancy, it is preferable to wait until the post-partum period to administer INH, unless the mother has HIV or a recent contact with active TB. Breastfeeding is not a contraindication to isoniazid.
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Is there a test for latent TB infection?

Oxford Immunotec - FAQs
The most reliable test for latent TB is the recently introduced T‑SPOT.TB test from Oxford Immunotec. An older, alternative test is the Tuberculin Skin Test (TST) which is performed using one of two methods; the Mantoux test or the Heaf test. The latter was used in the UK but has now been phased out in favour of the unlicensed Mantoux test. The T‑SPOT.TB assay is an in vitro diagnostic laboratory test that identifies Mycobacterium tuberculosis infection from a blood sample.
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What is the difference between TB infection and Active TB disease?

Communicable Diseases: Tuberculosis (TB) - Peel Public Healt...
When a person breathes the TB germ into their lungs, the body's defences (antibodies) usually destroy the TB germs or wall off the germs so no damage is done. People may not even know they have been infected. A skin test is able to detect TB anti-bodies. It shows whether someone has been exposed to the TB germ. People who have had sufficient contact with the TB germ will have a positive skin test 2-12 weeks after initial exposure. This is known as TB infection. TB infection is not contagious.
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What is the difference between TB disease and TB infection?

TB frequently asked questions
In most people who breathe in TB bacteria and become infected, the body is able to fight the bacteria to stop them from growing. The bacteria become inactive, but they remain alive in the body and can become active later. This is called TB infection. Most people who have TB infection will never develop TB disease. In these people, the TB bacteria remain inactive for a lifetime without causing disease.
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What is the difference between TB infection and TB disease?

Hawaii State Department of Health - www.hawaii.gov/health
People with TB infection (without disease) have the germ that causes TB in their body. They may have been carrying this germ for a short or a very long time, but they are not sick because the germ lies inactive in the body. The body's strong immune system has the germs under control. While the TB germs are inactive in your body, they cannot hurt you and you cannot spread them to other people. In fact, if you are infected by the TB germs, you probably will not know it and you will not feel sick.
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What is active TB disease?

Washington County -- Tuberculosis
The presence of TB bacteria in the body can lead to active disease (tuberculosis) if an infected person's immune system can't stop the bacteria from multiplying. Some people develop active TB disease soon after becoming infected, before their immune system can fight the TB bacteria. Other people that carry the bacteria may become sick later in life. Symptoms of active TB disease depend on where in the body the TB bacteria are growing.
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Tuberculosis (TB) Treatment & Control Clinic - Southern ...
TB bacteria become active if the immune system can’t stop them from growing. The active bacteria begin to multiply in the body and cause active TB disease. The bacteria attack the body and destroy tissue. If this occurs in the lungs, the bacteria can actually create a hole in the lung. Some people develop active TB disease soon after becoming infected, before their immune system can fight the TB bacteria.
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Oxford Immunotec - FAQs
When most people become infected with M. tuberculosis their own immune system limits the multiplication of the bacteria preventing the illness from developing. A small proportion of people who get infected are able to kill off the infection naturally. However, in many people the bacteria are not killed but are kept under control by the body's immune system. These people do not have any symptoms and cannot spread the disease. The infection is said to be latent (dormant).
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How is active TB disease treated?

Tuberculosis (TB) Treatment & Control Clinic - Southern ...
Active TB can almost always be cured with medicine, but the medicine must be taken as directed or you risk the bacteria becoming resistant to the medicine. Several medications are used at the same time because there are so many TB bacteria to be killed. TB bacteria die very slowly. It takes at least 6 months for the medicine to kill all of the TB bacteria. You will probably start feeling better after only a few weeks of treatment.
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What are the symptoms of active TB disease?

FAQ about Health
Please see the TB Internet Resource List for detailed information regarding testing, treatment, and active TB disease. Testing must be done in the USA. Test results from outside the United States will not be accepted. If you are tested in the United States prior to arriving at Kansas State University, bring the test results to Lafene Health Center as soon as you arrive at K-State. Yes, most health insurance will cover costs according to the coverage outlined in the policy.
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How is Latent TB Infection Different From TB Disease?

Frequent Questions - Public Health Department (DEP)
Latent TB infection means that a person has breathed in TB bacteria, or germs, and become infected with TB, but their body has been able to fight the infection and keep it from becoming active and making them sick. People with latent TB infection are not contagious and can not give TB to others.
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