If you have PS3 system version 1.6 or later, you will see a Folding@Home icon in the Network column of the XMB (PS3 menu). Just click on the icon and that's it. If you don't have 1.6 or later, please perform a system upgrade.

Folding@home is a distributed computing project that uses our computers to unravel the mysteries of the protein folding procedures. We are helping scientists at Stanford University to understand why and how proteins 'fold', so it will be easier for them to find cures for diseases like Alzheimers, Parkinsons, BSE, CJD, certain types of cancer, the influenza virus, Osteogenesis Imperfecta, etc.

Folding@Home is an example of a distributed supercomputer, like SETI@Home, United Devices, Entropia, Distributed.net, and many others. Distributed computing allows individuals to donate their computer time to build supercomputers 100 to 1000x greater than by traditional means.

A PS3, or Playstation 3 is a next generation gaming console that is being released by Sony. Before the PS3, there was the PS2 and the original Playstation. Both were very popular, and had more of a market share than Sega, Nintendo, and now Microsoft with their consoles.

The Folding@home project, especially the 2.x infrastructure and it's new updated 3.0 client, has been the major focus of the Pande Group's software development and methods research efforts over the last three years. The client and server software is more stable, versatile, and advanced than G@h Classic. Most importantly, as the research efforts of the Pande Group broaden and mature, and the Folding@home research project evolves, we need to avoid duplicating the efforts of our researchers.

For the Windows GUI version of Folding@Home, if Folding@Home has been installed using the official installer, there will be an "Uninstall" option available in the Folding@Home tab under the start menu. This will completely uninstall the software. For the console version of the software, you should be able to search for the FAH binary (called FAHConsole4.exe ) and delete the Folding@Home program.

We expect the PS3 to use about 200W while running Folding@Home. We have several PS3's running in our lab, running Folding@Home 24/7 and have had good results so far.

The PS3 right now runs what are called implicit solvation calculations, including some simple ones (sigmodal dependent dielectric) and some more sophisticated ones (AGBNP, a type of Generalized Born method from Prof. Ron Levy's group at Rutgers). In this respect, the PS3 client is much like our GPU client. However, the PS3 client is more flexible, in that it can also run explicit solvent calculations as well, although not at the same speed increase relative to PC's.

Yes. Reportedly, there could be as few as 150,000 units in North America right now, instead of the official 400,000.

MB of XDR Main RAM @ 3.2GHz and 256MB of GDDR3 VRAM @ 700MHz, or a total of 512MB for the entire system. The RSX graphics chip can actually use all 512MB of system RAM; it is not limited to the 256MB of GDDR3 RAM.

Currently Home is not a persistent world, so when you leave Home, all of your possessions go with you. For instance, it is not currently possible for other users to visit your apartment while you're not there. We are working on the persistent aspect of Home, and expect to implement it in the long term." Thats an odd choice, so I guess when people are in your "house" they are actually being hosted on that persons PS3? Odd choice (cheaper for sony too, so they don't have to waste bandwidth).

The PS3 should be released in November 2006 for North America, Europe, and Japan. For a detailed report with more information and details, click here to go to our Sony PS3 Release Date Page.

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You can download it from http://www.nsa.gov/selinux/ or you can use a distribution that already includes support for SELinux. Information about particular distributions can be found at the SELinux Sourceforge project.

The PS3 client will also support some advanced visualization features. While the Cell microprocessor does most of the calculation processing of the simulation, the graphic chip of the PLAYSTATION 3 system (the RSX) displays the actual folding process in real-time using new technologies such as HDR and ISO surface rendering. It is possible to navigate the 3D space of the molecule using the interactive controller of the PS3, allowing us to look at the protein from different angles in real-time.

Folding@home is a distributed computing project, that very simply stated, studies protein folding and misfolding. Protein folding is explained in more detail in the scientific background section.

Please only run Folding@home on machines you either own or on which you have the permission of the owner to run our software. Any other use of Folding@home violates our license agreement (and just isn't a good idea in general).

Yes. It can be configured to dial up automatically, or wait until you connect. There may be some problems with modems and the screen saver version. If you are experiencing any problems, please use the console version of Folding@home.

Yes. Please configure your Firewall or Proxy server in the configuration panel of the GUI client. You can reach the configuration panel by right clicking in the graphical display or by clicking on the task bar icon. Console clients can be configured by running the -config switch. If you are attempting to install the Windows graphical client or screen saver, and see "Setup is starting..

Yes, SETI@home and other distributed applications can be run alongside Folding@home, provided you have enough system memory. Some programs, including SETI@home run at a higher priority than Folding@home, which prevents FAH from progressing if it is run at the same time. If you notice the FAH client is not progressing, you can fix this by enabling the "Slightly Higher Priority" Option in the FAH cleint.

No, but Folding@home stresses the CPU quite a lot. It is important that you have sufficiently cooled your computer. This is something standard users should not have to worry about. With that being said, computers today are MADE for work. There is no proof suggesting that Folding@home has ever caused a CPU to fry, nor is there any evidence claiming that it will shorten the life of your CPU.

From the point of view of the computer, Folding@Home acts exactly like a web browser. It downloads files from the internet (with security checksums to ensure that they came from the official site). Indeed, it uses only port 80 (or 8080 if available) and talks to the servers via HTML, just like a web browser. From here, Folding@Home is different: it performs it's scientific calculation and then resends the data back.

We have taken swift action against illegal installations (such as Jethroted and Dales Kid) and are prepared for immediate action in case of other similar infractions. See below for 3rd party uninstallers. We have remotely terminated any further calculations for these clients so they will no longer use any significant CPU time or bandwidth. In addition, these accounts have been zeroed, no more points will be added, and investigations are on going.

Dr David Baker "The goal of Folding@home is to determine how proteins fold given the sequence of the protein, and to apply this knowledge to study protein folding related diseases." David Kim "Our project is similar to Predictor@home, in that we are trying to improve our methods by conducting research that is only possible with the computing power that a grid computing project can provide."

It won't affect them at all. The stats for Folding@home will continue on from where they are now, whether you run the F@h2.x client or upgrade to the F@h3.0 client.

For a current list of ongoing projects, see the LLG community projects page, the LLG committees page and the wiki ongoing projects page. Projects are all being done by volunteers, and therefore will be done when people finish them. We've promised dates in the past and invariably been wrong. The priorities are for the dictionary and the introductory materials book, with the latter more likely to come out earlier than the former.