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What are the benefits and risks associated with clinical trials?

AIDSinfo - Clinical Trials FAQ
You should know as much as possible about the research study. It is important for you to feel very comfortable asking questions and the staff should answer them in a way you can understand. A list of sample questions appears below.
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UConn Health Center Clinical Trials FAQs
There are both benefits and risks associated with clinical trials. By participating in a clinical trial, you can: The protocol may require a lot of your time for trips to the study site, treatments, hospital stays, or complex dosage requirements.
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Are There Risks or Side Effects in Clinical Trials?

UVa Cancer Center Clinical Trials
Yes. The treatments used in clinical trials can cause side effects and other health risks depending on the type of treatment and the patient's condition. Side effects vary from patient to patient. Because clinical trials are research into new areas of treatment, the risks involved are not always known ahead of time, though efforts have been made to find out what they might be. For this reason, trials can carry unknown dangers and side effects as well as hoped-for benefits.
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CTO FAQ's
Yes. The treatments used in clinical trials can cause side effects and risks depending on the type of treatment and the patient's condition. Side effects vary from patient to patient. Because clinical trials are research into new areas of treatment, the risks involved are not always known ahead of time, though efforts have been made to find out what these risks might be. For this reason, trials can carry unknown dangers and side effects as well as hoped-for benefits.
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What are the potential risks associated with clinical trials?

The Children's Tumor Foundation: Ending Neurofibromatosis Th...
There may be side effects or adverse reactions to medications or treatments. These might include headache, nausea, hair loss, skin irritation, or other physical problems. Sid effects may appear in the short- or long-term You may be required to devote a lot of your time for trips to the study site, treatments, hospital stays, or complex dosage requirements
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Osteoporosis Clinical Center & Research Program
The further a drug is in the testing process the more we know about it and its possible risks. Potential side effects differ between study medications. Before you are allowed to participate in a study, you will be advised of known possible side effects. In fact, some people who participate in our studies feel better informed of the side effects involved with prescription medication than the average person does.
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Are there long-term benefits of clinical trials?

Frequently Asked Questions-Clinical Trials-PPediatric Care
Clinical trials are important in the long-term treatment of childhood cancer, and discoveries made years ago through clinical trials are now the standard of care for conditions like leukemia and lymphoma. By participating in a trial, your child will help us develop improved treatments for future children with the same condition.
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What about clinical trials?

Pancreatic Cancer: Pancreatica - FAQ
Clinical trials are, ideally, a part of a system in which a series of scientifically-controlled experiments shepherd a plausible agent, combination of agents or procedure through a process whereby the efficacy of the agent or procedure is established or not. In the U.S. this process is overseen by the Food and Drug Administration ("FDA").
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Clinical Trials - Frequently Asked Questions - sleepdisorder...
Clinical trials are research studies that test new drugs and treatments for both safety and effectiveness in human beings. Clinical trials are carefully controlled and conducted by physicians, nurses, and other healthcare professionals. The results of clinical trials help determine if a particular treatment should be approved and made available for broader use to improve the overall standard of care.
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Weight loss surgery frequently asked questions (FAQ's).
We recommend using ObesityDirectory.com to choose a doctor, then ask your doctor about any clinical trials that you may be eligible for. They would be happy to help you. What are some of the reasons why a doctor might not treat me? Most treatment facilities will delay surgery, exclude from further consideration for surgery, or even cancel a scheduled operation for any patient who does not meet their minimum standards or who fails to follow through with instructions.
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Frequently Asked Questions about Eye Cancer
Clinical trials are studies of new kinds of cancer treatments. Doctors conduct clinical trials to learn how well new treatments work and what their side effects are. If they look promising, they are then compared to the current treatment to see if they work better or have fewer side effects. People who participate in these studies may benefit from access to new treatments before the Food and Drug Administration (FDA) approves them.
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What are some of the benefits and risks of participating in clinical studies or trials?

Cystic Fibrosis Foundation - FAQs About Clinical Trials
Being required to travel to the study site, receive treatments, stay in the hospital, or follow complex dosage requirements.
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What are the benefits and risks of participating in a clinical trial?

Clinical Trial FAQ's
Clinical trials that are well-designed and well-executed are the best approach for eligible participants to: The protocol may require more of their time and attention than would a non-protocol treatment, including trips to the study site, more treatments, hospital stays or complex dosage requirements.
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Shepherd Center: Frequently Asked Questions
Benefits: Well-designed, well-executed clinical trials may be the best way for certain qualified individuals to play a more active role in their health care, gain access to new experimental treatments before they become widely available, obtain expert medical care at leading healthcare facilities during the trial, and help others by contributing to medical research. The treatment may not be effective.
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What are the benfits and risks involved in clinical trials?

St. Joseph Mercy Oakland | For Healthcare Professionals | Re...
Improving the health of your friends, family and community through your contributions to medical research.
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What are the risks in clinical trials?

Tarnow Center - Psychiatry, Psychology, Education, and Couns...
The treatment may not be effective for you and your condition could worsen. If this happens, you will be withdrawn from the study and given immediate care. There may also be side effects associated with the treatment.
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Who can participate in clinical trials?

Arizona Alzheimer's Consortium
All clinical trials have guidelines about who can participate. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion criteria".
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Who monitors clinical trials?

Arizona Alzheimer's Consortium
Every clinical trial in the U.S. must be approved and monitored by an Institutional Review Board (IRB) to make sure the risks are as low as possible. An IRB is an independent committee of physicians, statisticians, community advocates, and others that ensures that a clinical trial is ethical and the rights of study participants are protected.
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How long will my participation in clinical trials last?

Arizona Alzheimer's Consortium
Every clinical trial is designed to address specific research questions. Duration of participation in clinical trials varies greatly depending on the type of study being conducted. Specific procedures are performed at specified time-points during the course of a clinical trial. Once you are formally enrolled and committed to a particular study, you should expect to participate anywhere from several weeks to several years.
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Will I get paid for my participation in clinical trials?

Arizona Alzheimer's Consortium
Each study conducted by the Arizona Alzheimer's Consortium institutions will vary greatly and compensation and/or reimbursement will be dependent upon the study's sponsor(s). Generally, however, participant compensation for participation in clinical trials is minimal and typically only covers costs such as mileage.
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Is there a fee for me to participate in clinical trials?

Arizona Alzheimer's Consortium
No. Participants receive study-related monitoring by a physician, study medications, and laboratory services for free for the duration of the study.
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Where can I find more information about clinical trials?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
It is important to understand the clinical trial process, as well as the features of the particular trial you are considering, before you agree to become a participant. For further information, the website clinicaltrials.gov includes a list of questions to ask about trial participation, and links to additional resources. Also, remember that you should discuss trial participation with your healthcare provider, as well as with your loved ones.
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Are the results of some clinical trials more reliable than others?

Cancer Treatments / Therapy Results, Survival Rates, Toxicit...
The reliability or "strength of evidence" of a clinical study depends on two major variables 1) who performed the study; 2) the design of the study. In respect to who performed the study, investigator bias can play a role in how the outcomes are reported. It is very difficult to determine if and when there are real conflicts of interest.
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How are Clinical Trials conducted?

UVa Cancer Center Clinical Trials
a cancer patient, you may take part in a clinical trial. This information is provided for you, your family and friends, to explain what clinical trials are and to help you make a decision about entering a trial. The time when cancer is diagnosed or when treatment decisions are being made is very difficult. It is often hard to understand or remember complex medical explanations. This information is meant to supplement what your doctors tell you.
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