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What causes Crohn's disease and ulcerative colitis?

CCFC Crohn's and Colitis - FAQ's
This is the question most often asked, but unfortunately the answer is still not known. It is likely that several factors work together. There may be an inherited predisposition that places an individual at higher risk of developing IBD. Research among families with more than one affected member will be important in discovering what accounts for this predisposition. Some trigger in the environment sets up the inflammation, and in the predisposed individual this does not go away.
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Inflammatory Bowel Disease : Frequently Asked Questions, Par...
Many researchers believe these diseases may be result of an "inherited predisposition" combined with a triggering environmental agent (possibly a bacteria or a virus). There is no simple, predictable pattern of inheritance though there is certainly some evidence to suggest that heredity has some role to play. For example, when two immediate family members both have IBD, the most common combination is mother-child, followed by sibling-sibling, with father-child being least common.
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a: How does IBS differ from Crohn's disease or ulcerative colitis?

Irritable Bowel Syndrome : Frequently Asked Questions - Heal...
The symptoms of IBS differ from the symptoms of Inflammatory Bowel Disease (IBD) in that there is NO trace of blood in the stool, or history of fevers or chills. IBS is a functional disporder, meaning that there is no demonstrable pathology in the colon or small bowel.
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How can you tell the difference between ulcerative colitis and Crohn's disease?

Ileostomy Surgery Information | Frequently Asked Questions
In most patients the gastroenterologist treating the patient can tell the difference by colonoscopy and biopsy. Some patients have "indeterminate colitis" with features of both conditions. These patients can also have a BCIR continent ileostomy.
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How are Crohn's disease and ulcerative colitis diagnosed?

Frequently Asked Questions About Inflammatory Bowel Disease ...
A thorough physical exam and a series of tests may be required to diagnose Crohn's disease or ulcerative colitis. The doctor may do an upper GI series to look at the small intestine. For this test, the person drinks barium, a chalky solution that coats the lining of the small intestine, before X-rays are taken. The doctor may also do a visual exam of the colon by performing either a sigmoidoscopy or a colonoscopy.
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Is ulcerative colitis an autoimmune disease?

Frequently Asked Questions
There is certainly a malfunction in the immune system that takes place in ulcerative colitis. However, immunosuppressive medications used to keep individuals from rejecting transplanted organs have shown less effectiveness in treating ulcerative colitis than in treating Crohn's disease.
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What causes ulcerative colitis?

Health Information
Although many theories about what causes ulcerative colitis exist, none has been proven. The cause of ulcerative colitis is unknown, and currently there is no cure, except through surgical removal of the colon. A theory suggests that some agent, possibly a virus or an atypical bacterium, interacts with the body's immune system to trigger an inflammatory reaction in the intestinal wall.
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Active Manuka Honey Internal Uses
Unfortunately the cause for Ulcerative Colitis has not been discovered yet. Many scientists believe that a virus or bacterium might be the cause for the inflammation. Certain foods or stress are definitely not the causes for Ulcerative Colitis, but they may aggravate or trigger the symptoms.
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Can Crohn’s disease or ulcerative colitis be fatal?

CCFC Crohn's and Colitis - FAQ's
Crohn's disease and ulcerative colitis are chronic diseases, meaning they recur throughout a person's life. The rate of recurrence is different for everyone, and some people can go years between disease relapses. Naturally, the severity of the disease varies from person to person, but most people lead active and full lives after being diagnosed. The life expectancy of those with Crohn's disease and /or colitis is normal. They are not considered terminal diseases.
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What is ulcerative colitis?

Health Information
Ulcerative colitis is an inflammatory bowel disease in which the inner lining of the large intestine (colon or bowel) and rectum become inflamed. Inflammation usually begins in the rectum and lower (sigmoid) intestine and spreads upward to the entire colon. Ulcerative colitis rarely affects the small intestine except for the lower section, the ileum. The inflammation causes diarrhea, or frequent emptying of the colon.
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Active Manuka Honey Internal Uses
Ulcerative Colitis (Colitis/ Proctitis) is a painful inflammatory bowel disease that causes ulcers in the lining of the large intestine. Because of the inflammation of the rectum the colon empties frequently. That results in frequent diarrhea. The inflammation gradually kills the healthy cells in the lining of the colon, producing bleeding ulcers in the intestinal wall that create pus. The disease mainly occurs between the ages 15 and 40, less frequently between the ages 50 and 70.
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What causes Crohn's disease?

Crohn's Disease
Doctors don't know what causes Crohn's disease. You may get it when the body's immune system has an abnormal response to normal bacteria in your intestine. Other kinds of bacteria and viruses may also play a role in causing the disease. Crohn's disease can run in families. Your chances of getting it are higher if a close family member has it. People of Eastern European (Ashkenazi) Jewish family background may have a higher chance of getting Crohn's disease.
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Crohn's Disease Frequently Asked Questions (FAQs)
The cause of Crohn's disease is unknown. However, research suggests that the body's defenses are operating against certain substances within the body or digestive tract. The foreign substances may cause the inflammation or may trigger the body's defenses to produce inflammation.
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What's the difference between Crohn's disease and ulcerative colitis?

C-Health
Crohn's disease (CD) and ulcerative colitis (UC) both damage the lining of the digestive system. They have many symptoms in common, including diarrhea (which may be bloody), abdominal pain and cramps, loss of appetite, malnutrition, and weight loss. However, they are separate medical conditions. The main differences between CD and UC are: UC affects only the colon (large intestine), while CD can affect any part of the digestive system, from the mouth to the anus.
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Do Crohn's disease and ulcerative colitis have the same cause?

Canadian Society of Intestinal Research • Ibd Faq
This has been a source of debate for many years. Some feel that the cause is the same and that different types of inflammation are due to the different locations of the disease process. Others feel that they are two unrelated disease processes and share only the fact that they involve intestinal tissue. More research is required to clarify this important question.
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How common are Crohn's disease and ulcerative colitis?

Canadian Society of Intestinal Research • Ibd Faq
There are about 10,000 new cases of IBD diagnosed each year in Canada. From the statistics to date, it would appear that the incidence of Crohn's disease is increasing. There are geographical and racial variations in the occurrence of both diseases for reasons that are not clear.
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How can you tell the difference between ulcerative colitis and Crohn's?

Brotman Continent Ostomy Center :: Frequently Asked Question...
Answer: In most patients, the difference between ulcerative colitis and Crohn's colitis can be made on the basis of colonoscopy, biopsies and barium enema X-ray. Answer: There should not be any pain with intubation. As long as there is adequate lubrication there will not be any irritation to the valve. If the intestinal waste is very thick, it may require thinning agents such as grape or prune juice or lactulose.
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To what extent are Crohn's disease and ulcerative colitis psychosomatic diseases?

Canadian Society of Intestinal Research • Ibd Faq
Since no one knows the causes of these diseases, no one can say for sure what role psychological factors play. Most physicians today believe that emotional problems do not cause Crohn's disease or ulcerative colitis. On the other hand, most would also agree that emotional factors may influence the course of the disease - just as they influence the course of most other chronic diseases.
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What affect has Crohn's disease and ulcerative colitis on pregnancy and conception?

Canadian Society of Intestinal Research • Ibd Faq
The fertility rate among women who have Crohn's disease or ulcerative colitis is essentially normal. The rate of spontaneous abortion is similar to that in the average population. The chances of having a normal child are also no different. In some patients, the illness worsens during pregnancy, while in others the illness might remain unchanged or even improve.
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Do people with Crohn's disease and ulcerative colitis develop cancer?

Canadian Society of Intestinal Research • Ibd Faq
Cancer of the small intestine, where Crohn's disease usually occurs, is an exceedingly rare disease. However, after many years of involvement with Crohn's disease, the incidence of cancer in the small intestine may be slightly higher than in the average population. More is known about the potential risk of cancer of the large intestine, or colon, as a complication of ulcerative colitis or Crohn's disease.
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What diet does the CCFC recommend for people with Crohn’s disease or ulcerative colitis?

CCFC Crohn's and Colitis - FAQ's
The relationship between IBD and diet continues to be researched. IBD affects people differently and while some foods are easily managed by one person, they could cause discomfort in others. Hence there is no 'one' recommended diet. It would be best for you to work together with your dietician, physician and/or gastroenterologist to arrive at what will work best for you. There have been cook books published for IBD patients.
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What is Crohn's disease?

Crohn's Disease
Crohn's disease is a lifelong inflammatory bowel disease (IBD). Parts of the digestive tract get swollen and have deep sores called ulcers. Crohn's disease usually is found in the last part of the small intestine and the first part of the large intestine. But it can develop anywhere in the digestive tract, from the mouth to the anus.
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Stomach Pain - Frequently Asked Questions
Crohns Disease causes inflammation of the digestive or gastrointestinal (GI) tract. This disease can affect any part of the entire digestive tract. Pain resulting from the inflammation can cause the intestines to empty frequently resulting in diarrhea. Crohns Disease is also called inflammatory bowel disease (IBD). IBD is a more general term for diseases that cause the inflammations in the intestines.
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Is ulcerative colitis life threatening?

Frequently Asked Questions
Ulcerative colitis is very rarely life threatening. Cases of toxic megacolon or excessive bleeding due a very severe flare-up where the colon swells up massively can be life threatening, which is why surgery is undertaken quickly if these conditions develop. Normally, ulcerative colitis is a chronic, life-long illness, characterized by periods of few symptoms, known as remission, and periods of very active disease, known as flare-ups. Ulcerative colitis is not a strictly genetic disease.
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Who is affected by ulcerative colitis?

Health Information
Although children and older people sometimes develop ulcerative colitis, it most often affects people ages 15 to 40. It affects males and females equally and appears to run in some families.
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Why is ulcerative colitis a concern?

Health Information
Ulcerative colitis requires long-term medical care. There may be remissions - periods when the symptoms go away - that last for months or even years. However, usually symptoms eventually return. Only in rare cases, when complications occur, is the disease fatal. If only the rectum and lower colon are involved, the risk of cancer is not higher than normal. However, the risk of colon cancer is greater than normal in children with widespread ulcerative colitis.
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What are the symptoms of ulcerative colitis?

Health Information
The following are the most common symptoms for ulcerative colitis. However, each child may experience symptoms differently. Symptoms may include: The symptoms of ulcerative colitis may resemble other conditions or medical problems. Consult your child's physician for a diagnosis.
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How is ulcerative colitis diagnosed?

Health Information
A thorough physical examination, including blood tests to determine whether an anemic condition exists, or if the white blood cell count is elevated (a sign of inflammation), is part of the diagnostic process. Symptoms that suggest ulcerative colitis may also be evaluated with the following procedures: colonoscopy - a test that uses a long, flexible tube with a light and camera lens at the end (colonoscope) to examine inside the large intestine.
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