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What causes the appetite and obesity problems in PWS?

QUESTIONS AND ANSWERS ON PRADER-WILLI SYNDROME
People with PWS have a flaw in the hypothalamus part of their brain, which normally registers feelings of hunger and satiety. While the problem is not yet fully understood, it is apparent that people with this flaw never feel full; they have a continuous urge to eat that they cannot learn to control. To compound this problem, people with PWS need less food than their peers without the syndrome because their bodies have less muscle and tend to burn fewer calories. No.
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What causes obesity?

Obesity FAQ - Special Sections > Weighed Down > The Issues |...
Obesity results from eating too many calories and not getting enough physical activity over a long period of time. This balance is affected by genes, metabolism, behavior, environment, culture and socioeconomic status.
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Eating Disorders FAQ self esteem for women helping women bui...
Obesity results when there is an imbalance between energy intake and energy expenditure. In other words, you consume more calories than you expend in your daily activities. There can also be medical causes for obesity, such as glandular irregularities. Many glandular problems are now medically treatable.
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Do diet medications work for the appetite problem in PWS?

QUESTIONS AND ANSWERS ON PRADER-WILLI SYNDROME
Unfortunately, no appetite suppressant has worked consistently for people with PWS. Most require an extremely low-calorie diet all their lives and must have their environment designed so that they have very limited access to food. For example, many families have to lock the kitchen or the cabinets and refrigerator.
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Obesity--What is it and What Causes it?

List of Health Problems Because of Obesity
This article contains information on obesity. The dangers and causes are discussed. It also talks about some ways of getting started on the path to living a healthy lifestyle. With canine obesity on the rise, the lifestyle we impose on our four legged friends has come increasingly under the spotlight. Here we look at how much exercise dogs should be getting, and the range of exercises available to dog owners.
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What kinds of behavior problems do people with PWS have?

QUESTIONS AND ANSWERS ON PRADER-WILLI SYNDROME
In addition to their involuntary focus on food, people with PWS tend to have obsessive/compulsive behaviors that are not related to food, such as repetitive thoughts and verbalizations, collecting and hoarding of possessions, picking at skin irritations, and a strong need for routine and predictability. Frustration or changes in plans can easily set off a loss of emotional control in someone with PWS, ranging from tears to temper tantrums to physical aggression.
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What causes being overweight and obesity?

Shrinking Violets Weight Loss FAQ's and diet myths
The main causes of being overweight or obese are eating too much and/or not being active enough. If you eat more calories than your body burns up, the extra calories are stored as fat. Everyone has some stored fat. Too much fat results in being overweight or obese. Other factors that may affect your weight include your genes (obesity tends to run in families), your metabolism (how your body processes food), your racial/ethnic group, and your age.
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What causes severe obesity?

Frequently Asked Questions (FAQs)
Severe obesity is most likely a result of genetic, psychological, environmental, social, and cultural influences that interact resulting in the complex disorder of both appetite regulation and energy metabolism. In obese persons, the set-point of stored energy is too high. This altered set-point may result from a low metabolism with low energy expenditure, excessive calorie intake, or a combination of both disorders.
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What causes morbid obesity?

Akron General Medical Center - Obesity Faq
Morbid obesity is likely the result of both genetic and environmental influences. Recent studies suggest that the tendency to have morbid obesity can be inherited. They also suggest that family cultural factors matter, especially those, which encourage high calorie food intake. (Top)
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The Bariatric Surgery Program at University Hospitals of Cle...
The disease is probably due to a combination of genetic and environmental factors. It certainly runs in families. The most recent studies suggest that the tendency for morbid obesity is inherited and that family cultural factors, which encourage high calorie food intake, also play a role. If one identical twin is morbidly obese, the other twin has a high likelihood of being morbidly obese as well; even if adopted into the home of non-obese individuals.
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Bariatric Surgery FAQ - BariatricEdge.com
The causes of morbid obesity are multiple and complex. Despite conventional wisdom, it is not simply a result of overeating. Research has shown that, in many cases, significant, underlying causes of morbid obesity are genetic, environmental, and social. Studies have demonstrated that, once the problem is established, efforts such as dieting and exercise programs have a limited ability to provide effective long-term relief. Back to Top
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FAQs
Obesity is generally defined as the condition of having a BMI greater than or equal to 30, which can be determined with a BMI calculator. Forty million Americans are obese, and 30% of men and 40% of women between the ages of 40 and 49 are at least 20% over their ideal weight. Obesity increases as people age.
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Frequently Asked Questions (FAQ's) about Weight Loss / Obesi...
The reasons for obesity are many and complex. It is not simply a result of overeating. Research has shown that in many cases a significant, underlying cause of morbid obesity is genetic. Studies have demonstrated that once the problem is established, efforts such as dieting and exercise programs have a limited ability to provide effective long-term relief.
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Weight Loss FAQ - Calorie Calculators and Guide to Burning F...
Obesity occurs when a person consumes more calories than their body can use. However, the underlying causes of obesity are thought to be more complex. Genetic, environmental, socio-economical, psychological, and medical factors may all contribute in varying degrees to developing obesity. Genetic Factors: The role of genetics in the development of obesity varies from person to person. Genes have been found to play a significant role in the regulation of body weight.
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Medifast Weight Control Centers
Thought at one time to be a simple problem and easily solved, obesity is now recognized as a complex and often chronic condition. Disagreement and debate still prevails on almost every key issue concerning obesity. Although the basic cause of obesity is an imbalance between calorie intake and energy expenditure, why this imbalance occurs is not always clear.
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Methodist Hospitals | Weightloss Center
Obesity is caused by an energy imbalance. Our genetic make up has not changed since the stone ages. Our genes require us to burn more calories than we consume in order to remain healthy and fit. However, today’s modern society affords us a copious supply of food and many labor-saving technologies which can virtually eliminate the need for physical activity
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What are some of the serious health problems linked to obesity?

Shrinking Violets Weight Loss FAQ's and diet myths
If you are overweight or obese, you are more likely to develop health problems such as heart disease, diabetes, and some types of cancer. The good news is that losing weight can improve how your heart works, lower your blood pressure, improve your cholesterol levels, and lower your chances of getting other health problems. Heart disease. Heart disease is the leading cause of death for both men and women in the United States.
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What are obesity associated health problems?

Frequently Asked Questions - Bariatric Solutions
Diabetes, High Blood Pressure, Obstructive sleep apnea (breathing problems during sleep), stroke, coronary artery disease, vascular disease, hyperlipidemia, certain cancers (breast, prostate, endometrial, colon), osteoarthritis, skin infections, leg swelling, psychological problems
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What causes orthodontic problems (malocclusions)?

SureSmile - Orthodontic FAQ's
Most malocclusions are inherited, but some are acquired. Inherited problems include crowding of teeth, excess space between teeth, extra or missing teeth, and a wide variety of other irregularities of the jaws, teeth and face. Acquired malocclusions can be caused by trauma, sucking on fingers or thumbs or pacifiers, airway obstruction by tonsils and adenoids, dental disease or premature loss of baby teeth or permanent teeth.
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What causes orthodontic problems?

Orthodontics and Braces FAQ's: Information on Orthodontic De...
Orthodontic problems are typically inherited, but they can also be acquired by developmental factors. Some of the most commonly inherited conditions include crooked teeth, crowded teeth and other irregularities of the teeth and jaw. Acquired problems can be caused by developmental factors such as thumb sucking, mouth breathing, and the premature loss of baby or permanent teeth.
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Read our FAQs about implant dentistry, dental implants, toot...
Orthodontic problems arise because of a disharmony in the development of the jaws, muscles and teeth. Many of the orthodontic problems we see are inherited, but environmental and behavioral factors can also play a part in abnormal development. Orthodontic treatment from Dr. Wooten can balance out the irregularities and correct overcrowding and other difficulties. Dr.
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What causes hemorrhoid problems?

Hemorrhoids, SVCMC; New York NY
Excessive pressure on the veins in the pelvic and rectal area causes hemorrhoid problems. As pressure increases, blood pools in veins and causes them to swell, stretching the surrounding tissue. Increased pressure can come from rushing to complete a bowel movement or from constipation or persistent diarrhea, if either causes too much straining during bowel movements.
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What is obesity?

Obesity FAQ - Special Sections > Weighed Down > The Issues |...
adult with a body mass index of 30 or higher is considered obese. Children are seldom classified as obese. Childhood obesity refers to children in the 95th percentile and above for their size among all other people their age.
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Weight loss surgery frequently asked questions (FAQ's).
Obesity results from the excess accumulation of fat that exceeds the body's skeletal and physical standards. According to the American Obesity Association, obesity is a disease. Obesity is defined as being 20% or more over ideal weight (BMI >25). Ideal weight is the weight associated with the longest life. Ideal weight tables show the ideal weight as it relates to gender and height.
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Is PWS inherited?

QUESTIONS AND ANSWERS ON PRADER-WILLI SYNDROME
Most cases of PWS are attributed to a spontaneous genetic error that occurs at or near the time of conception for unknown reasons. In a very small percentage of cases (2 percent or less), a genetic mutation that does not affect the parent is passed on to the child, and in these families more than one child may be affected. A PWS-like disorder can also be acquired after birth if the hypothalamic portion of the brain is damaged through injury or surgery.
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