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Frequently Asked Questions

How do M. D. Anderson patients pay for clinical trials?

Brian Nelson
The clinical trial sponsor (whether it is the government or a company) may pay for the experimental treatment, special testing, extra doctor visits, travel time and travel expenses. Some health insurance companies also will cover routine costs in clinical trials. Some health insurance companies will cover the costs of procedures that patients would have even if they were not in a clinical trial (routine costs).
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Who sponsors M. D. Anderson's clinical trials?

Brian Nelson
The U.S. National Cancer Institute (NCI) sponsors many of M. D. Anderson's clinical trials. Drug companies may also sponsor clinical trials. This is because these companies must show that their drugs and medical devices are safe and effective in order to receive FDA approval and become available to the public. M. D. Anderson and nonprofit organizations also sometimes sponsor clinical trials.
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Does M. D. Anderson have any information on clinical trials in complementary medicine?

CIMER - FAQ - M. D. Anderson Cancer Center
Yes, you may find this information by going to Clinical Trials in Integrative Oncology. For a listing of all clinical trials at M. D. Anderson, you can return to the M. D. Anderson Cancer Center Home Page, select "Patients and Public" and then "Clinical Trials". To learn more about complementary/integrative medicine, you can visit the Web site for the Place...of wellness here at M. D. Anderson Cancer Center (or see Mind-Body Approaches under Reviews of Therapies on this Web site). The Place..
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How does M. D. Anderson protect patients?

Brian Nelson
When conducting clinical trials, M. D. Anderson's most important responsibility is to protect patients through well-designed protocols, A protocol is a detailed plan that explains what will be done in a clinical trial and why. It outlines how many patients will participate, what medical tests they will receive and how often, and the treatment and monitoring plan. Researchers must follow the protocol approved by M. D. Anderson's Institutional Review Board (IRB).
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Will M. D. Anderson lead any clinical research at the Proton Therapy Center?

Proton Therapy Center - FAQ - Proton Therapy Center - Proton...
Every patient treated at the Proton Therapy Center will be placed on one of more than 25 new protocols related to tissue toxicity and optimal tumor dose to answer critical cancer questions and advance the science of proton therapy. This presents a unique opportunity to confirm the effectiveness of proton therapy as an adjunct to conventional therapy or in place of current treatments.
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Will you treat non-M. D. Anderson patients at the Proton Therapy Center?

Proton Therapy Center - FAQ - Proton Therapy Center - Proton...
Yes. The Center will treat patients from the surrounding Texas Medical Center as well as around the nation and the world. The majority of the patients are expected to come from M. D. Anderson, Texas and the United States.
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How many patients are using the device? In the US? Elsewhere? In clinical trials?

Alternative Medicine & High Blood Pressure, Natural Remedies...
Although the device represents a new class of treatment, it is not an alternative medicine treatment. Hypertension is a mainstream disorder and RESPeRATE has received clearance from the FDA as an adjunctive treatment for hypertension (together with other pharmacological and/or non-pharmacological interventions.) The device is also validated by numerous published peer reviewed studies and a renowned Scientific Advisory Board.
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Are there other Tarceva clinical trials available for patients with advanced NSCLC?

Lung Cancer Frequently Asked Questions - Tarceva.com
You can find information on additional clinical trials of Tarceva (erlotinib) by visiting ClinicalTrials.gov
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What types of cancers did patients have in registrational clinical trials?

About Kepivance®: Frequently Asked Questions
All patients had hematologic malignancies including non-Hodgkin's lymphoma, Hodgkin's disease, acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, or multiple myeloma.
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How will M. D. Anderson staff the Center?

Proton Therapy Center - FAQ - Proton Therapy Center - Proton...
The Division of Radiation Oncology will staff the center, just as it currently staffs other areas of the division such as the Radiation Treatment Center satellite facilities located throughout the Houston area.
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Will M. D. Anderson employees benefit from this program?

Tobacco Treatment Program - FAQ - M. D. Anderson Cancer Cent...
This program is offered only to M. D. Anderson patients. M. D. Anderson employees are not eligible for the Tobacco Treatment Program; however, employees can access tobacco cessation services through Employee Health & Well-being.
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What about clinical trials?

Pancreatic Cancer: Pancreatica - FAQ
Clinical trials are, ideally, a part of a system in which a series of scientifically-controlled experiments shepherd a plausible agent, combination of agents or procedure through a process whereby the efficacy of the agent or procedure is established or not. In the U.S. this process is overseen by the Food and Drug Administration ("FDA").
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Clinical Trials - Frequently Asked Questions - sleepdisorder...
Clinical trials are research studies that test new drugs and treatments for both safety and effectiveness in human beings. Clinical trials are carefully controlled and conducted by physicians, nurses, and other healthcare professionals. The results of clinical trials help determine if a particular treatment should be approved and made available for broader use to improve the overall standard of care.
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Weight loss surgery frequently asked questions (FAQ's).
We recommend using ObesityDirectory.com to choose a doctor, then ask your doctor about any clinical trials that you may be eligible for. They would be happy to help you. What are some of the reasons why a doctor might not treat me? Most treatment facilities will delay surgery, exclude from further consideration for surgery, or even cancel a scheduled operation for any patient who does not meet their minimum standards or who fails to follow through with instructions.
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Frequently Asked Questions about Eye Cancer
Clinical trials are studies of new kinds of cancer treatments. Doctors conduct clinical trials to learn how well new treatments work and what their side effects are. If they look promising, they are then compared to the current treatment to see if they work better or have fewer side effects. People who participate in these studies may benefit from access to new treatments before the Food and Drug Administration (FDA) approves them.
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What are clinical trials, and how do they affect mesothelioma patients?

Mesothelioma FAQ: Mesothelioma Treatment, Pleural Mesothelio...
A clinical trial is a research study using volunteers. A clinical trial tests the effectiveness and safety of a new procedure or drug, including proper dosage and side effects. Taking part in a clinical trial may prolong or improve a mesothelioma patient’s life. On the other hand, clinical trials deal with experimental drugs or procedures that may have negative results or be ineffective.
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Does M. D. Anderson Cancer Center have any programs in complementary medicine?

CIMER - FAQ - M. D. Anderson Cancer Center
M. D. Anderson Cancer Center does have some programs involving complementary/integrative therapies. You may learn about these programs by going to Educational Programs & Events on the CIMER Web site or to the Place...of wellness.
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How is the Proton Therapy Center structured? What is its relationship to M. D. Anderson?

Proton Therapy Center - FAQ - Proton Therapy Center - Proton...
M. D. Anderson's proton therapy facility was designed to meet the unique needs of cancer patients. Because of the large investment required to build and equip a proton center, M. D. Anderson together with partners ?The Styles Company and Sanders Morris Harris -- have formed a company to develop, own and operate the proton facility. The company, called Proton Therapy Center-Houston, Ltd., LLP., is a limited liability limited partnership jointly owned by M. D. Anderson and private investors. M. D.
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How does PTC Therapeutics identify patients with nonsense mutations for the clinical trials?

PTC Therapeutics
To confirm the diagnosis of a nonsense mutation for the clinical trials in cystic fibrosis, PTC Therapeutics employed the gene sequencing test offered by Ambry Genetics (www.ambrygen.com). For the clinical trial in Duchenne muscular dystrophy, we used the test offered by the University of Utah (http://www.genome.utah.edu/DMD/clinical_test.shtml).
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Who can participate in clinical trials?

Arizona Alzheimer's Consortium
All clinical trials have guidelines about who can participate. Using inclusion/exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion criteria".
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Who monitors clinical trials?

Arizona Alzheimer's Consortium
Every clinical trial in the U.S. must be approved and monitored by an Institutional Review Board (IRB) to make sure the risks are as low as possible. An IRB is an independent committee of physicians, statisticians, community advocates, and others that ensures that a clinical trial is ethical and the rights of study participants are protected.
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How long will my participation in clinical trials last?

Arizona Alzheimer's Consortium
Every clinical trial is designed to address specific research questions. Duration of participation in clinical trials varies greatly depending on the type of study being conducted. Specific procedures are performed at specified time-points during the course of a clinical trial. Once you are formally enrolled and committed to a particular study, you should expect to participate anywhere from several weeks to several years.
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Will I get paid for my participation in clinical trials?

Arizona Alzheimer's Consortium
Each study conducted by the Arizona Alzheimer's Consortium institutions will vary greatly and compensation and/or reimbursement will be dependent upon the study's sponsor(s). Generally, however, participant compensation for participation in clinical trials is minimal and typically only covers costs such as mileage.
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Is there a fee for me to participate in clinical trials?

Arizona Alzheimer's Consortium
No. Participants receive study-related monitoring by a physician, study medications, and laboratory services for free for the duration of the study.
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Where can I find more information about clinical trials?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
It is important to understand the clinical trial process, as well as the features of the particular trial you are considering, before you agree to become a participant. For further information, the website clinicaltrials.gov includes a list of questions to ask about trial participation, and links to additional resources. Also, remember that you should discuss trial participation with your healthcare provider, as well as with your loved ones.
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Are the results of some clinical trials more reliable than others?

Cancer Treatments / Therapy Results, Survival Rates, Toxicit...
The reliability or "strength of evidence" of a clinical study depends on two major variables 1) who performed the study; 2) the design of the study. In respect to who performed the study, investigator bias can play a role in how the outcomes are reported. It is very difficult to determine if and when there are real conflicts of interest.
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