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Frequently Asked Questions

What is the pituitary?

Pituitary Network Association - FAQ
The pituitary is a small, pea-sized gland located at the base of the brain that functions as "The Master Gland." From its lofty position above the rest of the body it sends signals to the thyroid gland, adrenal glands, ovaries and testes, directing them to produce thyroid hormone, cortisol, estrogen, testosterone, and many more. These hormones have dramatic effects on metabolism, blood pressure, sexuality, reproduction, and other vital body functions.
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What is a pituitary Tumor?

Pituitary Network Association - FAQ
A pituitary tumor is an abnormal growth of pituitary cells. Pituitary tumors can either be nonfunctional (that is they do not secrete hormones) or produce specific hormones, such as prolactin (causing infertility, decreased libido, and osteoporosis), growth hormone (causing acromegaly), ACTH (causing Cushing's), TSH (causing hypothyroidism), or be nonfunctional (that is they do not produce hormones).
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What are pituitary tumors?

Frequently Asked Questions about Pituitary Cancer
A pituitary tumor is a tumor that begins in the pituitary gland. Most pituitary tumors are not cancer. In fact, cancerous pituitary tumors are so rare that state and national cancer agencies keep no record of how many people get them each year. Benign (non-cancerous) pituitary tumors are also rare. About 3,000 people get them each year.
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What is the pituitary gland?

Frequently Asked Questions about Pituitary Cancer
The pituitary gland is a small gland located behind the nasal sinuses and above the roof of the mouth at the base of the skull. It is connected to the hypothalamus, a part of the brain. Together, the two control the production of many of the important hormones in the body. The pituitary gland sits in a tight bony space and has little room to grow or expand when swollen or if there is a tumor.
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Is this something associated with the damage to my pituitary gland?

Frequently Asked Questions-Page 4
CDI itself does not interfere with menstruation or fertility. However, it may be associated with these or other problems if the disease or injury that caused the DI also damages adjacent parts of the brain or pituitary where other hormones are normally produced. Head trauma is one of the things that can cause this kind of collateral damage, but it does not always do so. Therefore, each patient with CDI must be evaluated separately to determine if any of the other hormones have been affected.
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What causes the pituitary to malfunction?

Pituitary Network Association - FAQ
Tumors (overwhelmingly benign), inflammation, infections and injury can cause the gland to malfunction, as well as metastasis or spread of other tumors to the pituitary (rare). Radiation therapy to the brain can also cause normal pituitary cells to malfunction.
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How are pituitary tumors treated?

Pituitary Network Association - FAQ
It depends on the type of tumor and how far it has invaded into the brain, as well as the patient's age and overall health. Three kinds of treatment are used: surgery (removing the tumor during an operation), radiation therapy (using high-dose x-rays/proton beams to kill tumor cells) and drug therapy to shrink and sometimes eradicate the tumor. Drugs can also block the pituitary gland from making too much hormone.
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What are the symptoms of pituitary tumors?

Frequently Asked Questions about Pituitary Cancer
Pituitary tumors that affect hormones may cause a variety of symptoms, which are related to high hormone levels and production. These symptoms will be different in children than in adults. Growth hormone-secreting adenomas in children may cause: Other more rare kinds of pituitary tumors cause other symptoms. It is important for anyone who is experiencing any unusual symptoms to see their doctor.
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What are the symptoms of a pituitary tumor?

This depends on the type of tumor and the size of the tumor. A large tumor may cause loss of vision, particularly peripheral vision, if it compresses the optic chiasm (where the optic [eye] nerves converge). Headache may also occur; the type of headache varies from patient to patient. Headache may occur with a large or a small tumor.
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What is a pituitary adenoma?

Pituitary Tumor Treatment Center FAQ - UCSF Department of Ne...
A pituitary adenoma is a tumor-that is, a growth of tissue in which cells multiply in an uncontrolled manner. Adenomas are located just next to, or within the pituitary gland. The adenoma can be much smaller than the gland when the symptoms it causes become noticeable and the adenoma is diagnosed. Most pituitary adenomas are 'microadenomas', which measure 3 to 9 mm (1/8 to 3/8 of an inch) in diameter, although a few patients have 'macroadenomas', which are 10 mm or larger in diameter.
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What are the pituitary hormones and what do they do?

Pituitary Society - Public Site - Information about the pitu...
ACTH deficiency: ACTH stimulates the adrenal glands to produce cortisol. Cortisol is essential for life. When cortisol is inadequate, patients experience fatigue, weakness, weight loss, nausea and vomiting, low blood pressure and may develop shock and die unless treated. TSH deficiency: TSH stimulates the thyroid gland to produce thyroid hormone. Low thyroid hormone causes fatigue (loss of energy), weight gain, constipation, dry skin, and feeling cold.
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Why are pituitary disorders so hard to diagnose?

Pituitary Network Association - FAQ
Pituitary disorders can cause a wide spectrum of symptoms, both hormonal and neurological, due to its location near the brain, the intracranial nerves and blood vessels and because of the vital hormonal control that the gland provides. Diagnosis of pituitary disease may be extremely difficult because it's often confused with other disorders. It is dependent on symptoms, signs on examination, blood tests and MRI findings. Direct access to the pituitary can only be reached at surgery.
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Which hormones are secreted by the anterior pituitary?

Pituitary Network Association - FAQ
Thyroid Stimulating Hormone (TSH) causes the thyroid gland to produce and release thyroid hormones. Thyroid hormone controls the basal metabolic rate and plays an important role in growth and maturation. Thyroid hormones affect almost every organ in the body. Adrenocorticotropic Hormone (ACTH) triggers the adrenals to release the hormone cortisol, which regulates carbohydrate, fat, and protein metabolism and blood pressure.
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How prevalent are pituitary tumors/disease?

Pituitary Network Association - FAQ
Autopsy reports and radiologic and MRI evidence from around the globe indicate that one out of every five people worldwide has a pituitary tumor. The earliest study took place in 1936, when Dr. R.T. Costello of the Mayo Foundation conducted a cadaver study and found pituitary tumors in 22.4 % of the population (Costello R.T. Subclinical adenoma of the pituitary gland. Am. J. Pathol. 1936; 12:205-214). Statistics have not changed much ever since.
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Are all pituitary tumors created equal?

Pituitary Network Association - FAQ
No. There are more than a dozen very different disorders that result from pituitary tumors and disease. For example, if a tumor forms in an ACTH secreting pituitary cell, it could result in the overproduction of cortisol (Cushing's Disease) or the underproduction of cortisol (adrenal insufficiency, often referred to as Secondary Addison's Disease).
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What are the risk factors for pituitary tumors?

Frequently Asked Questions about Pituitary Cancer
Certain factors can make one person more likely to get a pituitary tumor than another person. These are called risk factors. In some cancers, doctors have identified risk factors that can be avoided, such as smoking or sun exposure. With pituitary tumors, doctors are not sure what exactly causes pituitary tumors and only one risk factor has been identified. Most people who get a pituitary tumor have no known risk factors.
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Which hormones are produced and/or controlled by the posterior pituitary or hypothalamus?

Pituitary Network Association - FAQ
Oxytocin stimulates contractions of the uterus during labor and the ejection of milk during breast-feeding. Antidiuretic Hormone (ADH) increases reabsorption of water into the blood by the kidneys and therefore decreases urine production. Also referred to as Vasopressin.
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What happens if the pituitary produces either too much or too little of these hormones?

Pituitary Network Association - FAQ
imbalance occurs, leading to more than a dozen disorders of the endocrine system. Deficiency of thyroid hormone, adrenal cortical hormone (cortisol) or antidiuretic hormone (vasopressin) is rapidly life-threatening. In patients with abnormalities of the other hormones, quality of life is significantly compromised.
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Can a microadenoma in the pituitary cause CDI or does it have to be a macro?

Frequently Asked Questions-Page 5
Microadenomas do not cause CDI. However, infiltrative diseases of the pituitary, which can mimic micros on MRI, can. Given your symptoms, you should have tests to determine whether you do, indeed, have CDI.
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What are the symptoms of the various types of pituitary tumors?

Hi. I'm a nursing student and I recently had a male patient, 64 yrs. old, who is diagnosed with Diabetes Mellitus type 1, obesity, hypertension, a right below-the-knee amputation due to osteomyelitis, depression, chronic renal insufficiency, and a few other things, including poor wound healing. He has the typical Cushing's body type and the buffalo hump. He has no striae on his abdomen.
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What is the role of the pituitary gland?

Focus Families, Septo-optic dysplasia, Optic nerve hypoplasi...
The pituitary, or master gland, controls the function of many other glands - the thyroid, adrenals, ovaries, testes. It also produces growth hormone and anti-diuretic (water saving) hormone.
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What are anterior pituitary peptides and where do they come from?

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The anterior pituitary peptides are bio-engineered parts of molecules from glandular extracts. Glandular products have been used in Europe for years and are usually taken from animal sources such as lamb, bovine or porcine. These are pharmaceutical grade and especially prepared from disease free herds and flocks.
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Will not then an early pituitary adenoma be undetected ?

Neuroophthalmology FAQ
No, It can produce endocrine problems by which it may be suspected and then subsequently detected by CT scan.
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