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How likely are lewisite and mustard-lewisite to cause cancer?

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The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the Environmental Protection Agency (EPA) have not classified Lewisite as to its carcinogenicity. Both the DHHS and IARC have classified the blister agent H/HD (the sulfur mustard used in the Mustard-Lewisite mixture) as a human carcinogen. We to not know whether the Mustard-Lewisite mixture might also be a human carcinogen.
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How might I be exposed to lewisite and mustard-lewisite?

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People that are potentially exposed to Lewisite or Mustard-Lewisite are soldiers who might be exposed to chemical weapons or people who work at military sites where these compounds are stored.
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What happens to lewisite and mustard-lewisite when it enters the environment?

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In air, blister agents Lewisite and Mustard-Lewisite will be broken down by compounds that are found in the air, but they may persist in air for a few days before being broken down. Lewisite and Mustard-Lewisite will be broken down in moist soil quickly, but small amounts may evaporate.
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How can lewisite and mustard-lewisite affect my health?

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If you breathe Lewisite or Mustard-Lewisite vapors, your airways will immediately become irritated. You could experience burning pain in the nose and sinuses, laryngitis, cough, shortness of breath, nausea, and vomiting. You could also experience airway tissue damage and accumulation of fluid in your lungs, which could result in death.
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How does lewisite and mustard-lewisite affect children?

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There is no information on children exposed to Lewisite or Mustard-Lewisite, but children would probably be affected in the same ways as adults. We do not know whether children differ from adults in their susceptibility to these blister agents.
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How likely is tetryl to cause cancer?

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The International Agency for Research on Cancer (IARC), the Department of Health and Human Services (DHHS), and the Environmental Protection Agency (EPA) have not reviewed tetryl to determine whether it is likely to cause cancer.
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Is there a medical test to show whether I've been exposed to lewisite and mustard-lewisite?

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There are no specific tests to indicate whether you have been exposed to Lewisite or Mustard-Lewisite. The presence of arsenic in the urine could indicate if you have been exposed to one of these blister agents. Airborne Exposure Limit (as recommended by the Surgeon General's Working Group, U.S. Department of Health and Human Services) of 0.003 milligrams of Lewisite and Mustard-Lewisite per cubic meter of air (0.003 mg/m3) has been established as a time-weighted average (TWA) for the workplace.
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How likely is 4,4'-methylenedianiline to cause cancer?

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The International Agency for Research on Cancer has determined that 4,4'-methylenedianiline is possibly carcinogenic to humans. A study on people exposed to bread contaminated with 4,4'-methylenedianiline did not show an increased risk of cancer. An animal study showed cancer of the liver and thyroid after animals drank water over their lifetimes containing 4,4'-methylenedianiline.
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How likely are nitrogen mustards to cause cancer?

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The International Agency for Research on Cancer (IARC) has classified nitrogen mustard HN-2 as probably carcinogenic to humans, based on evidence that it causes leukemia in humans and cancers of the lung, liver, uterus, and large intestine in animals.
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How likely is phosgene oxime to cause cancer?

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The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the Environmental Protection Agency (EPA) have not classified phosgene oxime for carcinogenicity. There is no information to determine whether exposure to phosgene oxime might cause cancer.
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How likely are total petroleum hydrocarbons (TPH) to cause cancer?

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The International Agency for Research on Cancer (IARC) has determined that one TPH compound (benzene) is carcinogenic to humans. IARC has determined that other TPH compounds (benzo[a]pyrene and gasoline) are probably and possibly carcinogenic to humans. Most of the other TPH compounds are considered not to be classifiable by IARC.
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How likely is hexachlorobenzene to cause cancer?

ATSDR - ToxFAQs™: Hexachlorobenzene
The U.S. Department of Health and Human Services (DHHS) has determined that hexachlorobenzene may reasonably be expected to be a carcinogen. Animals that ate hexachlorobenzene for months or years developed cancer of the liver, kidneys, and thyroid. There is no strong evidence that it causes cancer in people. A factory worker who breathed air for several years that contained many chemicals, but mostly hexachlorobenzene, developed liver cancer.
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How likely are CDFs to cause cancer?

ATSDR - ToxFAQs™: Chlorodibenzofurans (CDFs)
The Department of Health and Human Services, the International Agency for Research on Cancer, and the Environmental Protection Agency (EPA) have not classified CDFs for carcinogenicity. It is not definitely known if CDFs cause cancer in people. There are no cancer studies in animals that ate or breathed CDFs.
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How likely is manganese to cause cancer?

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There are no human cancer data available for manganese. Exposure to high levels of manganese in food resulted in a slightly increased incidence of pancreatic tumors in male rats and thyroid tumors in male and female mice. The Environmental Protection Agency (EPA) has determined that manganese is not classifiable as to human carcinogenicity.
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How likely is mercury to cause cancer?

ATSDR - ToxFAQs™: Mercury
There are inadequate human cancer data available for all forms of mercury. Mercuric chloride has caused increases in several types of tumors in rats and mice, and methylmercury has caused kidney tumors in male mice. The EPA has determined that mercuric chloride and methylmercury are possible human carcinogens.
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How likely are polychlorinated biphenyls (PCBs) to cause cancer?

ATSDR - ToxFAQs™: Polychlorinated Biphenyls (PCBs)
Few studies of workers indicate that PCBs were associated with certain kinds of cancer in humans, such as cancer of the liver and biliary tract. Rats that ate food containing high levels of PCBs for two years developed liver cancer. The Department of Health and Human Services (DHHS) has concluded that PCBs may reasonably be anticipated to be carcinogens. The EPA and the International Agency for Research on Cancer (IARC) have determined that PCBs are probably carcinogenic to humans.
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How likely are pyrethrins and pyrethroids to cause cancer?

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There is no evidence that pyrethrins or pyrethroids causes cancer in people or in animals. The International Agency for Research on Cancer (IARC) has determined that the carcinogenicity to humans for three pyrethroids (deltamethrin, fenvalerate, permethrin) is not classifiable.
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Which cancer treatments are most likely to cause male infertility?

Lance Armstrong Foundation: Physical Effects Male Infertilit...
Usually, the cancer treatment, not the actual cancer, damages a man’s fertility. Radiation and chemotherapy kill cells that are in the middle of dividing and growing, when they are easier to damage. Cancer cells divide much more often than most normal body tissues, so they are killed off while normal cells survive. However, hair and sperm cells also grow constantly, making them sensitive to chemotherapy or radiation.
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How likely is 1,1,1-trichloroethane to cause cancer?

Trichloroethane: Frequently Asked Questions Frequently Asked...
No information is available to show that 1,1,1-trichloroethane causes cancer. The International Agency for Research on Cancer (IARC) has determined that 1,1,1-trichloroethane is not classifiable as to its human carcinogenicity.
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How likely is chlordane to cause cancer?

ATSDR - ToxFAQs™: Chlordane
The International Agency for Research on Cancer has determined that chlordane is not classifiable as to its carcinogenicity to humans. Studies of workers who made or used chlordane do not show that exposure to chlordane is related to cancer, but the information is not sufficient to know for sure. Mice fed low levels of chlordane in food developed liver cancer.
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How likely are nitrophenols to cause cancer?

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The Department of Health and Human Services, the International Agency for Research on Cancer, and the Environmental Protection Agency (EPA) have not classified the nitrophenols as to their human carcinogenicity. animal study found no evidence of cancer when 4-nitrophenol was applied to the skin of mice, and no studies in people are available.
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How likely is asbestos to cause cancer?

ATSDR - ToxFAQs™: Asbestos
The Department of Health and Human Services (DHHS), the World Health Organization (WHO), and the EPA have determined that asbestos is a human carcinogen. It is known that breathing asbestos can increase the risk of cancer in people. There are two types of cancer caused by exposure to asbestos: lung cancer and mesothelioma. Mesothelioma is a cancer of the thin lining surrounding the lung (pleural membrane) or abdominal cavity (the peritoneum).
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How likely is 1,3-butadiene to cause cancer?

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The Department of Health and Human Services has determined that 1,3-butadiene may reasonably be anticipated to be a carcinogen. This is based on animal studies that found increases in a variety of tumor types from exposure to 1,3-butadiene. Studies on workers are inconclusive because the workers were exposed to other chemicals in addition to 1,3-butadiene.
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How likely is arsenic to cause cancer?

ATSDR - ToxFAQs™: Arsenic
Several studies have shown that ingestion of inorganic arsenic can increase the risk of skin cancer and cancer in the liver, bladder, and lungs. Inhalation of inorganic arsenic can cause increased risk of lung cancer. The Department of Health and Human Services (DHHS) and the EPA have determined that inorganic arsenic is a known human carcinogen. The International Agency for Research on Cancer (IARC) has determined that inorganic arsenic is carcinogenic to humans.
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How likely is ammonia to cause cancer?

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We do not know whether ammonia can cause cancer in humans or in laboratory animals. The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified ammonia for carcinogenicity.
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How likely is phenol to cause cancer?

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It is not known if phenol causes cancer in people. Cancer occurred in mice when phenol was applied to the skin several times each week for the lifetime of the animal. Phenol did not cause cancer in mice or rats when they drank water containing it for 2 years. The International Agency for Research on Cancer (IARC) has determined that phenol is not classifiable as to its carcinogenicity to humans.
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What types of cancer are most likely to cause involuntary weight loss?

Prosure.ws - FAQ About ProSure and Cancer Patients
Cancers that are frequently associated with involuntary weight loss include cancers of the colon, esophagus, head and neck, kidney, lung, pancreas, rectum, and stomach, as well as advanced breast cancer, leukemia, ovarian cancer, and prostate cancers.
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How likely is beryllium to cause cancer?

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The Department of Health and Human Services (DHHS) and the International Agency for Research on Cancer (IARC) have determined that beryllium is a human carcinogen. The EPA has determined that beryllium is a probable human carcinogen.
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How likely is boron to cause cancer?

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The Department of Health and Human Services, the International Agency for Research on Cancer, and the Environmental Protection Agency (EPA) have not classified boron as to its human carcinogenicity. One animal study found no evidence of cancer after lifetime exposure to boric acid in food. No human studies are available.
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