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How many patients are enrolled in this trial, and at how many clinical centers?

SCD-HeFT: Statistics for sudden cardiac death and FAQs on la...
There are 2,521 patients enrolled in the trial, at 148 centers across the U.S., Canada (10), and New Zealand (1).
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What is a clinical trial?

Clinical Trial FAQ's
A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments.
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VisionCare FAQs
A clinical trial is a study to test the safety and effectiveness of a new drug or medical device in patients. A physician supervises the research and follows a clinical protocol, or study plan. Studies of new medical devices or new drugs also require approval of the U.S. Food and Drug Administration (F.D.A.).
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UVa Cancer Center Clinical Trials
In cancer research, a clinical trial is a study conducted with cancer patients, usually to evaluate a new treatment. Each study is designed to answer scientific questions and to find new and better ways to help cancer patients. The search for good cancer treatments begins with basic research in laboratory and animal studies. The best results of that research are tried in patient studies, hopefully leading to findings that may help many people.
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Cystic Fibrosis Foundation - Frequently Asked Questions
Once researchers have shown that a new drug is safe and potentially effective in the laboratory, a study is designed to evaluate it in people. This study is known as a clinical trial. If the Food and Drug Administration approves the clinical trial, the study can begin in people. Researchers find volunteers with CF who fit the criteria for the specific clinical trial. Some trials, for instance, may be targeted only at children or only at people with digestive problems.
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Frequently Asked Questions-Clinical Trials-PPediatric Care
A clinical trial is a research study that uses volunteers to test new methods of screening, prevention, diagnosis or treatment of a disease. A cancer clinical trial is a research study that is designed to answer important questions about cancer diagnosis, treatment and prevention.
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Frequently Asked Questions
The ACR provides a list of clinical trials led by ACR members, and provides links to other sites that list clinical trial information. You may also wish to consult your rheumatologist for information on clinical trials for which you may be eligible.
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Do cancer patients ever receive placebos (inactive medicines) in a clinical trial?

Brian Nelson
Cancer patients in a clinical trial always receive the best standard treatment available or a new treatment that researchers believe is as good or better. A placebo is a substance that looks like medicine, but is not. Cancer patients are given placebos in a randomized trial only under unusual circumstances.
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What is expected of patients in a clinical trial?

Clinical Trials in Vision Research [NEI Clinical Studies]
Patients in a clinical trial are expected to have eye exams and other tests. You may also need to take medications and/or undergo surgery. Depending upon the treatment and the examination procedure, you may need a hospital stay. You may have to go back to the medical facility later for followup examinations. These exams help find out how well the treatment is working. Followup studies can take months or years.
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Should I consider participating in a clinical trial?

Lung Cancer.org :: Frequently Asked Questions
This is something to discuss with your medical team. There are many benefits to participating in clinical trials and there are also some risks. The clinical trial section of this website has more information to help you make up your mind on this important question. Special thanks to the members of CancerCare of Long Island lung cancer patient support group for their contributions to the list of questions.
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Can I participate in more than one clinical trial at a time?

Arizona Alzheimer's Consortium
No. You can participate in only one intervention study at a time so that the efficacy of the substance being tested will not be confused with the effects of another intervention. It may be possible to volunteer for an observational study and an interventional study simultaneously. For additional information on clinical trials, please visit: http://www.clinicaltrials.gov
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Clinical Trial FAQ's
All clinical trials have guidelines about who can participate. Using inclusion/ exclusion criteria is an important principle of medical research that helps to produce reliable results. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion criteria".
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What happens during a clinical trial?

Clinical Trial FAQ's
The clinical trial process depends on the kind of trial being conducted. The clinical trial team includes doctors and nurses as well as social workers and other health care professionals. They check the health of the participant at the beginning of the trial, give specific instructions for participating in the trial, monitor the participant carefully during the trial, and stay in touch after the trial is completed.
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What exactly is a clinical trial? Should I participate in one?

Breast Cancer FAQ
Clinical trials are studies that help evaluate a new treatment. Clinical trials attempt to answer scientific questions and to find new and better ways to help cancer patients. An institutional review board (IRB) carefully reviews the study before patients begin participation in the clinical trial. Also, some studies are reviewed by government agencies, such as the National Cancer Institute (NCI) and the National Institutes of Health (NIH).
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Why is the IMT-002 clinical trial being conducted?

VisionCare FAQs
The trial is being conducted to evaluate the safety and effectiveness of the telescope implant. Patients will be observed for changes in vision and side effects. Data will be tabulated and submitted for product approval.
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Who conducts a clinical trial?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
Clinical trials are typically sponsored by government agencies (such as the National Institutes of Health), and by biotechnology, pharmaceutical, and medical device companies that develop new drugs and treatments. Clinical trials take place at a variety of investigative sites such as hospitals, medical centers, and doctors' offices. As a participant, your contact is the healthcare provider (investigator) at the investigative site.
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What is a "blind" or "masked" clinical trial?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
You may hear that a treatment is being tested through a "blind" or "masked" clinical trial. This means that participants don't know whether the treatment they are receiving is the target treatment or a control treatment. If a trial is "double-blind" or "double-masked," that means that neither the trial participants nor the investigators know who is receiving the target versus control treatments.
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What happens to the clinical trial data?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
Researchers review the clinical trial data after each phase to determine if the next phase should begin. After Phase III has been completed and the treatment judged to be safe, effective, and an improvement upon existing treatments, the treatment is submitted for review by the FDA. The FDA may then approve the treatment for use in the general public or mandate that additional research be conducted. Results of clinical trials are sometimes published in medical journals.
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How are clinical trial participants protected?

Clinical Trials - Frequently Asked Questions - sleepdisorder...
IRB Review: Before a treatment is administered to patients in a clinical trial, all aspects of the treatment are thoroughly reviewed by a qualified panel of experts, called an Institutional Review Board, or IRB. Informed Consent: Before participating in a trial, you are asked to provide your "informed consent." This means that you agree to participate in the clinical trial, and that you have been provided with extensive information about the trial.
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UNC ACTU Homepage
Clinical trials are carefully-monitored research studies in which health professionals test new therapies (e.g., new medications, combinations of established medications, or diagnostic tests) on human subjects after laboratory and animal studies have suggested that such therapies may be effective in humans. They have contributed to our knowledge of HIV/AIDS, aided the development of safer and more effective medications, and led to dramatic improvement in the lives of people living with HIV/AIDS.
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Why Would a Patient Be Interested in a Clinical Trial?

UVa Cancer Center Clinical Trials
Patients take part in clinical trials for many reasons. Usually, they hope for benefits for themselves. They may hope for a cure of disease, a longer time to live, a way to feel better. Often they want to contribute to a research effort that might help others. Based on what researchers learn from laboratory studies, and sometimes earlier clinical studies and standard treatments as well, they design a trial to see if a new treatment will improve on current treatments. The hope is that it will.
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Are You Eligible for a Clinical Trial?

UVa Cancer Center Clinical Trials
Every clinical trial is designed to answer a set of research questions. If you fit the guidelines for a trial, you may be eligible to take part. Each study enrolls patients with certain types and stages of cancer and certain health status. A study that involves two or more treatments can yield reliable answers only if all the patient cases are the same so they can be compared with each other.
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What Is It Like To Be a Patient in a Clinical Trial?

UVa Cancer Center Clinical Trials
Whether cancer patients are in a research study or not, they face a new world of medical terms and procedures. For some people, myths and fears of experimentation or of being a guinea pig come with the idea of clinical trials. And, surely, there are fears of the unknown. Understanding what is involved can ease some of your anxieties.
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What Protection Do You Have as a Patient in a Clinical Trial?

UVa Cancer Center Clinical Trials
The ethical and legal codes that govern medical practice apply to clinical trials. In addition, most clinical research is federally regulated or federally funded (at least in part), with built-in safeguards to protect patients. These safeguards include regular review of the protocol (the study plans) and the progress of each study by researchers at other places.
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Rochester Clinical Research
A clinical trial (also called clinical research) is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments.
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