What treatments are available for children who have Hereditary Angioedema?
HAE Frequently Asked QuestionsFortunately, most prepubescent children with HAE do not suffer from frequent attacks and infrequent flares affecting the abdomen can be managed by using pain relievers and anti nausea agents. The small number of severely affected children who experience frequent and severe attacks must be managed on a case by case basis.
Related QuestionsWhat is Hereditary Angioedema?
HAE Frequently Asked QuestionsHereditary Angioedema (HAE) is a very rare and potentially life threatening genetic condition that occurs in about 1/10,000 to 1/50,000 people. HAE symptoms include episodes of edema (swelling) in various body parts including the hands, feet, face, and airway. In addition, patients often have bouts of excruciating abdominal pain, nausea, and vomiting that is caused by swelling in the intestinal wall. Airway swelling is particularly dangerous and can lead to death by asphyxiation.
Related QuestionsWhat causes Hereditary Angioedema attacks?
HAE Frequently Asked QuestionsMost attacks occur spontaneously with no apparent reason, however anxiety, stress, minor trauma, surgery, and illnesses such as colds and flu have been cited as triggers. Trauma to the oral cavity caused by dental procedures make HAE patients particularly vulnerable to airway attacks. Patients have also reported swelling in extremities following typing, prolonged writing, pushing a lawn mower, hammering, shoveling, and other physical activities.
Related QuestionsHow is Hereditary Angioedema diagnosed?
HAE Frequently Asked QuestionsMost cases of angioedema are not HAE because swelling attacks are typically caused by something other than C1-inhibitor deficiency, usually an allergic reaction. Laboratory analysis of blood samples or genetic testing is required to establish the HAE diagnosis. There are two specific blood tests that confirm HAE: C1-inhibitor functional common form of the disease--Type I--is characterized by low quantitative levels of C1-inhibitor and affects about 85% of patients.
Related QuestionsHow long do Hereditary Angioedema attacks last?
HAE Frequently Asked QuestionsPatients often report tingling or tightness at the site where edema will occur thirty minutes to several hours later. In some cases, this sensation can be present twelve to twenty four hours before the onset of swelling. Approximately one fourth of HAE patients experience a flat, non itching red blotchy rash both before and during an attack. The edema itself usually lasts for twenty four to seventy two hours, but the length of an attack can range from four hours to four or more days.
Related QuestionsWhen are Hereditary Angioedema attacks considered serious?
HAE Frequently Asked QuestionsSwelling of the extremities is uncomfortable and, according to some patients, can be painful and debilitating depending on the location of the edema. Attacks that involve the face and throat must be taken seriously and medical treatment should be sought without delay. Swelling of the throat can close the air passage and cause death by suffocation. The symptoms of an impending airway obstruction include difficulty swallowing and a change in voice pitch.
Related QuestionsHow is Hereditary Angioedema treated?
HAE Frequently Asked QuestionsTreatment of acute attacks Clinicians generally recommend long term therapy for patients who experience more than one attack per month, or who believe that the disease significantly interferes with their life style. The present drugs of choice for long-term therapy are 17 alpha alkylated androgens such as danazol, and oxandrolone (Oxandrin). 17 alpha alkylated androgens produce an increase in C1-inhibitor levels, but the exact mechanism of how they do so has not been precisely defined.
Related Questionswhat age do attacks of Hereditary Angioedema start?
HAE Frequently Asked QuestionsThe age of HAE onset varies considerably, however, in one study, half of the patients reported onset of their symptoms by the age of seven, and over two thirds became symptomatic by the age of thirteen. There also seems to be an increased frequency of attacks during puberty or adolescence.
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What non-operative treatments are available for children with CP?
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Related QuestionsIs Hughes Syndrome hereditary, can my children be tested?
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Related QuestionsIs the Antiphospholipid Antibody Syndrome hereditary, should my children be tested?
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Related Questionsf: What are some of the psychological treatments available?
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