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Frequently Asked Questions

Are umbilical cord blood cells the same as embryonic stem cells?

Cord Blood Donation: Frequently Asked Questions
No, umbilical cord blood cells are taken from the baby's umbilical cord and placenta after the baby is born, and not from an embryo.
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Where can I donate umbilical cord stem cells?

FAQs [Stem Cell Information]
NIH cannot accept donated umbilical cord stem cells from the general public. The National Marrow Donor Program maintains a Web page on donating cord blood at http://www.marrow.org/NMDP/cord_blood_bank_list.html, and the International Cord Blood Society has one at http://www.cordblood.org/index.php?rm=common_page&id=10.
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When And How Do You Collect The Cord Blood Stem Cells?

Umbilical Cord Blood Frequently Asked Questions
The collection process takes place after delivery when the cord has been separated from your newborn infant. In no way does it interfere with the birth of your baby. Your attending physician, nurse or midwife collects the cord blood utilizing a sterile kit provided by Cord Partners. The collected cord blood is sealed in a specially designed package and delivered to our laboratory for testing and processing. Finally, the sample is cryogenically stored until it needs to be retrieved.
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Are umbilical cord blood stem cells the same as embryonic stem cells?

Cord Blood Rights - A Mother's Right to Know
No, umbilical cord stem cells and embryonic stem cells are totally different. Sometimes there is a misperception due to the recent publicity about embryonic stem cells and the controversy about the federal government funding research for embryonic stem cells. Embryonic stem cells are involved with discharged fetuses either from a miscarriage or an abortion. These fetuses are the source for embryonic stem cells which are being used for research purposes.
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Are stem cells found in umbilical cord blood?

Center for Stem Cell Biology - Research Q and A | Life Scien...
Yes, one type of stem cell is found in umbilical cord blood. This type, known as a hematopoietic or blood-forming stem cell, is more specialized than embryonic stem cells, but it has the ability to generate all types of blood and immune system cells. It does not have the ability to form cells in other tissues, like the brain.
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What are the possible future uses for umbilical cord blood stem cells?

Cells for Life
Encouraging research is taking place in many areas of medicine. Stem cell research into diseases such as stroke, multiple sclerosis, lupus, diabetes, Parkinson's, Alzheimer's disease, muscular dystrophy and other autoimmune diseases have all shown promising results. Research has been based on the plasticity of stem cells and the potential to direct them into other cell types, such as heart, nerve, liver and pancreas cells.
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What are umbilical cord blood cells?

Umbilical Cord Blood Donation FAQs
Umbilical cord blood (UCB), once regarded as biological waste, has become an accepted source of hematopoietic stem cells/hematopoietic progenitor cells (HSCs/HPCs), similar to those found in bone marrow and peripheral blood.
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How Long Has Science Known About Stem Cells in Umbilical Cord Blood?

BabyCord Jordan
Although cord blood has only recently received widespread media attention, the first successful cord blood transplant took place in France in 1988, for a child with Fanconi’s Anemia, a rare congenital anemia. In 1991, a transplant was performed on a child with chronic Myelogenous Leukemia. Both transplants were successful, opening the door to cord blood transplantations for situations in which traditional bone marrow had been routinely used.
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How Long Has NECBB Been Banking Umbilical Cord Blood Stem Cells?

BabyCord Jordan
NECBB has been processing and storing umbilical cord blood stem cells since 1995. Our laboratory, New England Cryogenic Center, has been a pioneer in the field of cryogenics since 1982 and of all of the cord blood banks in North America, NECBB is the most experienced in cryopreservation methods. Driven by innovation and strong ethics, President John Rizza represents the third generation in his family to lead NECBB. Our Medical Director, Hans Klingemann, M.D., Ph.D.
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What are the benefits of using hematopoietic stem cells (HSCs) from umbilical cord blood (CB)?

PLURISTEM - GIVING LIFE A BETTER CHANCE
v CB transplant patients may have a higher survival rate, a higher quality of life after transplant and less frequent hospitalization due to complications such as Graft versus host disease (GVHD).
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Are cord blood stem cells different than other stem cells?

Cord Blood - Frequently Asked Questions
Cord blood stem cells are different from other stem cells. Stem cells from Umbilical cords are the youngest of all the stem cells, created by a live birth. Another form of stem cells come from embryo's. These embroyonic stem cells are not currently being used to treat humans. A third type of stem cells is found in bone marrow, which are adult stem cells.
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What makes cord blood stem cells unique?

Umbilical Cord Blood - Umbilical Cord Blood Banking
Cord blood stem cells have a number of significant advantages over other sources of stem cells (i.e., bone marrow): results in a lower rate of severe graft-vs-host disease (a major complication in stem cell transplants), and In addition, cord blood is "privileged" or unexposed to most diseases, which can make bone marrow from an adult more difficult to use in transplantation.
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Who can use the preserved cord blood stem cells?

Umbilical Cord Blood - Umbilical Cord Blood Banking
The preserved cord blood stem cells are, of course, available as a perfect match for the child from whose umbilical cord they were collected. Because there is a 1-in-4 chance of a perfect match with a sibling, parents may choose to make the cord blood available to siblings or potentially other family members who may need them. That decision is theirs alone.
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How long can cord blood stem cells be stored?

Umbilical Cord Blood - Umbilical Cord Blood Banking
Sufficient years have not passed to prove the absolute length of time; however, it is believed that stem cells can be successfully stored long term, perhaps decades, in a cryopreserved form. A recent study of cord blood at Indiana University demonstrated its viability after 15 years of cryogenic storage. Bone marrow has been stored for decades and has remained viable; there is no reason to believe that the same would not be true of cord blood.
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What are the current medical uses of umbilical cord blood?

Graduate School of Biomedical Sciences | Stem Cell Research ...
Umbilical cord blood stem cells are mostly used in stem cell transplantation to replace bone marrow cells. For reasons yet unknown, these cells pose less of a risk for rejection when compared to bone marrow stem cells. Due to the limited amount of cord blood, there is generally an insufficient number of cells for adult transplants.
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Why do parents save their children's umbilical cord blood?

Graduate School of Biomedical Sciences | Stem Cell Research ...
Umbilical cord blood is stored because it has a higher number of hematopoietic stem cells than bone marrow. Mothers generally save their babies' umbilical cord blood in case something is wrong, such as the baby needing a stem cell transplant while he or she is still a child. If, for example, the baby develops leukemia, he or she could be infused with his or her own umbilical cord blood.
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What is an umbilical cord blood unit? And how is it used in transplant?

Cord Blood Donation: Frequently Asked Questions
A cord blood unit is the term used for the blood collected from the umbilical cord and placenta after a baby is born. Cord blood is rich in blood-forming cells that can be used in transplants for patients with leukemia, lymphoma and many other life-threatening diseases. Cord blood is one of three sources of cells used in transplant; the other two are bone marrow and peripheral (circulating) blood (also called peripheral blood stem cell or PBSC transplants).
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If I donate umbilical cord blood is it always stored?

Cord Blood Donation: Frequently Asked Questions
The NMDP is committed to building an inventory of high-quality cord blood units to provide the best possible result for patients. When donated cord blood meets these standards for transplant, it will be stored and listed on the NMDP Registry: The cord blood unit must be large enough (contain enough blood-forming cells) for a transplant. If there are too few cells, the cord blood may be used for research to improve transplants for future patients or it may be discarded.
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Who controls the use of the preserved cord blood stem cells?

Umbilical Cord Blood - Umbilical Cord Blood Banking
Until the child is of legal age, the parents, as the child's guardians, have control over the stem cells. No stem cells will be released by Cryo-Cell without the parents' consent initially, and later the child's consent, once they reach legal age.
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What are the advantages of cord blood stem cells?

Healthcord - FAQs for Physicians
The regenerative potential of stem cells is greater in cells obtained from earlier stages of differentiation. Umbilical cord blood stem cells are relatively accessible at birth, and have been demonstrated to be at an earlier stage of differentiation relative to adult stem cells derived from bone marrow or mobilized peripheral blood, while not being associated with the practical and ethical concerns of harvesting embryonic stem cells, particularly forautologous use.
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How long can umbilical cord stem cells be kept frozen?

Cells for Life
Many years and possibly for the life time of the baby. Current research has shown stem cells to be viable for at least 15 years from the time of freezing.
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Why are cord blood stem cells preferred over bone marrow stem cells?

Cord Blood Banking FAQs - Family Cord Blood Services
Cord blood stem cells offer many advantages over other stem cells, especially bone marrow stem cells, including: Cord blood is a rich and non-controversial source of stem cells. The collection procedure is quick and very safe and poses no risk or discomfort to mother or baby Cord blood stem cells transplants cause less Graft vs.
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Are cord blood stem cells different than other types of stem cells?

Cord Blood Stem Cell - Frequently Asked Questions
Yes. Umbilical cord blood stem cells are the "youngest," safely available stem cells and they are the product of another miracle - a live birth. Freezing these cells essentially stops the clock and prevents aging and damage that may occur to the cells later in life. Another source of stem cells, embryonic stem cells, has been at the heart of heated debate. Currently, embryonic stem cells are not being used to treat humans.
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Can hematopoietic stem cells form cells other than blood and immune cells?

Graduate School of Biomedical Sciences | Stem Cell Research ...
This is a controversial topic. While some scientists have reported evidence that hematopoietic stem cells can repair cardiac tissue, others have proven otherwise. Another research group reported that the bone marrow contained cells that could repair the liver. Later studies showed that the bone marrow cells did not form liver cells, but rather fused with those cells. Despite these negative results, interesting new information has been gained.
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