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What causes Crohn's disease?

Crohn's Disease
Doctors don't know what causes Crohn's disease. You may get it when the body's immune system has an abnormal response to normal bacteria in your intestine. Other kinds of bacteria and viruses may also play a role in causing the disease. Crohn's disease can run in families. Your chances of getting it are higher if a close family member has it. People of Eastern European (Ashkenazi) Jewish family background may have a higher chance of getting Crohn's disease.
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Crohn's Disease Frequently Asked Questions (FAQs)
The cause of Crohn's disease is unknown. However, research suggests that the body's defenses are operating against certain substances within the body or digestive tract. The foreign substances may cause the inflammation or may trigger the body's defenses to produce inflammation.
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What causes Crohn's disease and ulcerative colitis?

CCFC Crohn's and Colitis - FAQ's
This is the question most often asked, but unfortunately the answer is still not known. It is likely that several factors work together. There may be an inherited predisposition that places an individual at higher risk of developing IBD. Research among families with more than one affected member will be important in discovering what accounts for this predisposition. Some trigger in the environment sets up the inflammation, and in the predisposed individual this does not go away.
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What is Crohn's disease?

Crohn's Disease
Crohn's disease is a lifelong inflammatory bowel disease (IBD). Parts of the digestive tract get swollen and have deep sores called ulcers. Crohn's disease usually is found in the last part of the small intestine and the first part of the large intestine. But it can develop anywhere in the digestive tract, from the mouth to the anus.
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Stomach Pain - Frequently Asked Questions
Crohns Disease causes inflammation of the digestive or gastrointestinal (GI) tract. This disease can affect any part of the entire digestive tract. Pain resulting from the inflammation can cause the intestines to empty frequently resulting in diarrhea. Crohns Disease is also called inflammatory bowel disease (IBD). IBD is a more general term for diseases that cause the inflammations in the intestines.
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What Causes Crohn Disease?

Crohn Disease FAQs Medical Reference Medical Encyclopedia In...
We do not know what causes the abnormal inflammation in the digestive tract. Experts believe that it is caused by an unknown triggering event in susceptible people. We do not know what makes a person susceptible, except that about 20-30% of people with Crohn disease have relatives with the disease—in other words, Crohn disease runs in the family. In the other 70-80% of cases, there is no family connection.
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Is Crohn's disease an autoimmune disease?

Frequently Asked Questions
A malfunction in the immune system is certainly a part of Crohn's disease. This may be an inability to "turn off" the immune system after it "turns on" for an appropriate reason. Or, the immune system may "turn on" for the wrong reason. Immunosuppressive medications used to keep individuals from rejecting transplanted organs have been shown to be effective in treating Crohn's disease. These factors have led many researchers to characterize Crohn's disease as autoimmune.
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Inflammatory Bowel Disease
Crohn's disease (CD) is an ongoing health problem that usually causes inflammation deep in the walls of the large intestine (colon) and/or the small intestine. But CD can affect any part of the digestive tract from the mouth to the anus. The inflammation usually causes abdominal pain and diarrhea. In other cases CD may cause constipation. Nearly half of all CD cases involve both the small and large intestine.
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What are the symptoms of Crohn's disease (CD)?

Inflammatory Bowel Disease
The symptoms of CD depend upon what part of the digestive system is affected. Since CD usually occurs in the last part of the small intestine (ileum) and in the nearby part of the colon, the most common symptoms are pain and tenderness in the abdomen, especially the lower right side and diarrhea. The symptoms of Crohn's disease may be mild or severe. And they often come and go.
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What are the complications of Crohn's disease (CD)?

Inflammatory Bowel Disease
In some people with CD, swelling and scar tissue thicken the bowel wall. This can close off the intestines causing an intestinal blockage. Intestinal blockages cause constipation, bloating, and other problems. Sometimes the ulcers of CD can break through the walls of the intestine. They then create tunnels or fistulas between the involved intestine and another part of the intestine or nearby organs. Fistulas usually occur in other parts of the intestines or the bladder, vagina, or skin.
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How is Crohn's disease (CD) diagnosed?

Inflammatory Bowel Disease
If you think you might have CD, talk to your doctor. She will use your health history, a physical exam, and several tests to figure out if you have CD. Blood tests: A sample of blood is studied in a lab to find signs of inflammation and anemia (low iron levels). Upper Gastrointestinal (GI) Series with Small Bowel Follow-Through: The patient drinks a chalky liquid that contains barium. Then x-rays are taken. Barium shows up on x-rays.
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Is Crohn's disease life-threatening?

Frequently Asked Questions
Crohn's disease is very rarely life threatening. Normally, Crohn's disease is a chronic, lifelong illness characterized by sporadic flare-ups separated by periods of remission. Occasionally, a complication such as a severe abscess or a large fistula connecting the intestine to another internal organ can set the stage for a life-threatening infection. In addition, Crohn's disease may require surgery; all surgical procedures involve the risk of life-threatening complications.
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How do you cope with Crohn's disease?

Crohn's Disease
Having Crohn's disease can be stressful. The disease affects every part of your life. Seek support from family and friends to help you cope. Get counseling if you need it. Many people with inflammatory bowel diseases look to alternative treatments to improve their well-being. These treatments have not been proven effective for Crohn's disease, but they may help you cope. They include massage, supplements such as vitamins D and B12, and herbs like aloe and ginseng.
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How will Crohn's disease affect pregnancy?

Crohn's Disease
The cause of Crohn's disease is unknown. Studies suggest that this and other inflammatory bowel diseases may result from an abnormal response by the body's immune system to normal intestinal bacteria.1 Disease-causing bacteria and viruses also may play a role in causing the condition. Crohn's disease can run in families, so some people may be more likely than others to develop the condition when exposed to something that triggers an immune reaction.
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Who gets Crohn's disease?

Crohn's Disease Frequently Asked Questions (FAQs)
It is estimated that up to 1.4 million Americans may be affected with inflammatory bowel disease (IBD). Of those people, 500,000 have Crohn's disease. Gastroenterologists diagnose Crohn's disease in men and women of all ages — including people in their seventies and eighties; however, the majority of cases are diagnosed before age 30 in men and women of Northern Europe and North America. Studies have shown that family history may play a role in the patterns of diagnosis of Crohn's disease.
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What is the role of diet in Crohn's disease?

Crohn's Disease Frequently Asked Questions (FAQs)
Depending on the severity of the disease, some patients need to restrict their diet all the time, others just some of the time, and still others may eat a normal, unrestricted diet. Avoiding a large number of foods can lead to disinterest in eating due to boredom, which can lead to reduced energy levels and subsequent weight loss.
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What Causes Crohn's Disease and Who Gets It?

h1 align=center>Frequently Asked Questions
There are many theories about what causes Crohn's disease, but none has been proven. One theory is that some agent, perhaps a virus or a bacterium, affects the body's immune system to trigger an inflammatory reaction in the intestinal wall. Although there is a lot of evidence that patients with this disease have abnormalities of the immune system, doctors do not know whether the immune problems are a cause or a result of the disease.
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Crohn's disease is an inflammatory bowel disease (IBD), the ...
The most popular theory is that the body's immune system reacts to a virus or a bacterium by causing ongoing inflammation in the intestine.
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Are the diagnostic tests used to find out if I have Crohn's disease painful?

Frequently Asked Questions
The level of discomfort varies with the activity of the disease. For most people, both barium enema and sigmoidoscopy entail some discomfort, but little pain. These tests can be painful, however, for a person experiencing a flare-up. A colonoscopy is a more painful procedure. Because of that, doctors use a combination of a sedative and a painkiller, known as "conscious anesthesia," when performing this procedure.
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Should I be worried about colon cancer if I have Crohn's disease?

Frequently Asked Questions
Statistical evidence does show that people with Crohn's disease have a slightly higher incidence of colon cancer than the general population does. For this reason, doctors begin regularly screening those with Crohn's disease about 12 years after diagnosis if the disease is confined to the small intestine, and eight years after diagnosis if there is disease in the colon.
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How is HUMIRA different from other medications that treat Crohn's disease?

Questions About HUMIRA and Crohn's Disease
HUMIRA is a medication that is taken by injection. And once your doctor shows you how to take HUMIRA, the injections can be taken in the convenience of your own home. After your initial starting doses, you only need to take one injection of HUMIRA every other week.
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How does Crohn's disease affect daily life?

Crohn's Disease Frequently Asked Questions (FAQs)
People who have Crohn's disease are affected in different ways, depending on the severity of their individual cases. Although Crohn's is a serious, chronic disease, many patients respond well to treatment and live productive, active lives, even though they may be hospitalized from time to time, or require periodic medication to control symptoms.
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