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What would be the advantage of germ-line gene therapy?

Questions and Answers About Gene Therapy
In the case of hereditary illness, successful germ-line gene therapy would have the potential to eliminate a genetic defect, such as hemophilia, from an entire family line with a single procedure. How long will it be until gene therapy is widely available? No one knows for sure, but within the next decade, genetic science will move closer toward finding treatments for various diseases.
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What is gene therapy?

Genomics|Frequently Asked Questions
Gene therapy is a technique for correcting faulty genes responsible for disease development. To learn more about gene therapy visit the Human Genome Project website.
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Frequently Asked Questions - FAQs
Gene therapy is a new approach to stem cell transplantation. Instead of finding a donor who is enough of a match to your child to donate bone marrow stem cells or umbilical cord blood stem cells, the transplant is done using the child's own cells. The appropriate cells are removed from the patient with ALD, the correct genetic sequence is inserted into those cells, and they are then put back into the patient.
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What about gene therapy? Is it a treatment for people with CF?

Cystic Fibrosis Foundation - Frequently Asked Questions
When scientists found the most common gene that causes CF in 1989, there was much excitement about the possibility of developing gene therapy. Gene therapy is the process by which healthy genes are delivered into cells and tissues of the body using such “vehicles” as a specially engineered virus. Researchers need to add enough healthy genes to override the effects of the defective ones.
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How can I use this test to eliminate the defective gene from my line?

Optigen - Frequently Asked Questions
Find out everything you can about your dog--then breed or don't breed according to the absence or presence of traits and health considerations you have no control over. Don't let the traits you can control dictate your breeding decisions. You now have control over prcd-PRA. An OptiGen-tested "Carrier" or "Affected" dog can be bred to a "Normal/Clear" dog without producing affected offspring. "Carrier" pups can be bred again to "Normal/Clear"s.
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What is the advantage of aspirin therapy with Ecotrin??

Ecotrin - The Safer* Aspirin - Answers to your Frequently As...
Only Ecotrin? is always safety coated. The enteric coating helps keep Ecotrin? aspirin intact until it reaches the small intestine. Ecotrin? dissolves in the small intestine, unlike plain or buffered aspirin that dissolve in the stomach. This makes it safer for the stomach than plain or buffered aspirin.
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Who was the youngest child treated with Gene Therapy for Canavan disease?

Canavan Research Illinois - Frequently Asked Questions About...
Max Randell made medical history in September 1998 when he became the youngest person in the world to receive experimental gene therapy for a neurodegenerative disease. Max was one of four children (of 15 treated) to generate new myelin as a result of this trial. All the participants showed quality of life improvements.
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What is the possibility of there being a genetic cure (or gene therapy) for NDI in the future?

Frequently Asked Questions-Page 4
Eventually, there may be a genetic cure for NDI since it should be one of the genetic disorders for which it is easiest to deliver the normal gene to the correct tissue. Even so, this type of treatment is likely to be years away since there are ethical and technical issues that have to be resolved first.
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What is the advantage of home infusion therapy?

Frequently Asked Questions | Penn Home Infusion Therapy | Pe...
Until the 1980s, infusion therapy was administered only at health care facilities, as an inpatient service. Individuals requiring lifelong therapy were not able to maintain normal lifestyle and work activities. Home infusion is a safe and effective alternative to inpatient care for many patients. Penn Home Infusion Therapy performs a thorough patient and home assessment to ensure that home infusion therapy is an appropriate method of treatment.
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What is Time Line Therapy??

Strategies for pain, anxiety, stress (Annapolis, Baltimore)
Time Line Therapy? is an effective tool of self-growth, confidence reinforcement, and personal dreams achievement. It helps us realize the root cause of negative emotions and trauma to let our unconscious mind explain and redefine the meaning of past events. By changing the emotions that attach to the event, we can eliminate negative emotions like guilt, anger, and frustration.
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What is the Germ?

Flour & Grain : Grain Chain Club
The embryo of the wheat plant with a radicle which can grow into roots and plumule which can develop into stems, leaves and ears. (The germ is present in wholemeal flour and can be added to white or brown flour (10%) to make wheatgerm flour).
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Will gene therapy or stem cell transplant save our child's life?

Frequently Asked Questions - FAQs
Gene therapy is not yet available outside the confines of a very small, preliminary clinical trial in France. Stem cell transplantation, either using umbilical cord blood stem cells or bone marrow stem cells from a matched donor, has been used successfully to arrest the progress of ALD in some boys with the disease. The treatment has serious risks of its own.
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How Does Gene Therapy Work?

Audience Results
The Cancer Genetics Network has affiliated institutions located throughout the United States and lists contact information. The CGN seeks to enroll individuals from minority populations, or who are at high risk for ovarian, colon or renal cell cancer, and families with multiple tumors. Human germline manipulations are those made to the genes of our germinal or reproductive cells (the egg and the sperm).
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How do I name a new gene?

Frequently Asked Questions
Researchers who want to reserve a new S. cerevisiae gene name do so through SGD. The name is shown on the appropriate SGD Locus Page as 'reserved', and after publication the name becomes the standard gene name. SGD maintains a detailed list of guidelines for choosing and reserving new gene names, and for the resolution of conflicts over gene names. A web form is available for submitting gene name reservations.
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What is the HLA-B27 gene?

About - Frequently Asked Questions About Ankylosing Spondyli...
HLA-B27 is a perfectly normal gene found in 8% of the general population. Generally speaking, no more than 2% of people born with this gene will eventually get spondylitis. The gene itself does not cause spondylitis, but people with HLA-B27 are more susceptible to getting spondylitis. If a family member had spondylitis and you test positive for the HLA-B27 gene, your chance of getting the disease increases to 20%, if you are under age 40.
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What is the advantage of per-line pricing?

Medical Transcription Services Company: USMedTrans | FAQ
Familiarity. This is the traditional way of paying for medical transcription. It is most appropriate for customers who use the US MedTrans medical transcription service to handle in-house transcription overflow or to augment another service.
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WHAT IS ON-LINE ADVISEMENT AND WHO CAN TAKE ADVANTAGE OF IT?

CHHS Student Services Center at Georgia Southern University
Yes--we offer online advisement after your initial meeting with an advisor. Check our online advisement page for details.
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Is there an advantage to applying on line?

Scholarships: Frequently Asked Questions - Grand Rapids Comm...
Yes, you will receive immediate notification that your scholarship application has been submitted and will be notified if you have failed to complete a required section of the form. You will still need to follow up with the college regarding your Financial Information Form.
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How could gene therapy be used to treat cancer?

Questions and Answers About Gene Therapy
Scientists are working on ways to genetically alter immune cells that are naturally or deliberately targeted to cancers. They are interested in arming such cells with cancer-fighting genes and returning them to the body, where they could more forcefully attack the cancer. Clinical trials along these lines are in progress for the treatment of melanoma. Alternatively, cancer cells can be taken from the body and altered genetically so that they elicit a strong immune response.
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How could gene therapy be used to treat AIDS?

Questions and Answers About Gene Therapy
Gene therapy could be used to make immune cells resistant to HIV (the AIDS virus). It could also be used to help patients destroy HIV and HIV-infected cells by increasing the body's immune response to these elements. Results from the ADA trial support the idea that genetically altered lymphocytes or stem cells might help prevent immune system failure in AIDS patients. T-lymphocytes enhanced with genes that block the spread of HIV could be tested in humans soon.
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What is the process by which gene therapy experiments receive approval?

Questions and Answers About Gene Therapy
A proposed experiment, or protocol, must pass through at least two review boards at the scientists' institution and must be approved by that institution. The protocol must then be approved by the Recombinant DNA Advisory Committee (RAC) of the National Institutes of Health (NIH) and be signed by the NIH director. All protocols must also receive the approval of the U.S. Food and Drug Administration.
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What scientific developments led up to gene therapy?

Questions and Answers About Gene Therapy
One crucial step in the evolution of gene therapy occurred in the early 1950s, when James Watson and Francis Crick elucidated the structure of DNA. Other major steps included the cracking of the genetic code in the 1960s and the discovery in the 1970s of restriction enzymes, which enabled researchers to isolate specific genes from DNA and to begin to develop recombinant DNA (gene-splicing) technology.
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Can gene therapy help with other,non-genetic diseases?

Questions and Answers About Gene Therapy
Yes. Many common threats to our health, including hypertension, heart disease, Alzheimer's disease and juvenile diabetes, actually have genetic components. People often have a genetic tendency toward a disease (such as when several family members have cancer). Someday, people in affected families may be able to use gene therapy to reduce their risks of developing a disease.
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