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Frequently Asked Questions

Should healthy bison that are MCF virus positive by serology or PCR be culled?

Malignant Catarrhal Fever, Frequently Asked Questions on Bis...
There is no reason at this time why such animals should be culled. An important question we are trying to answer is whether healthy test-positive bison are at a significantly higher risk of developing MCF compared to healthy test-negative bison.
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Why should I use a serology test instead of PCR?

Biotrin International
almost 100% of the population are sero positive for HHV-6, it is important to distinguish latent HHV-6 infections from active infections. PCR will detect HHV-6 viral DNA but it is unable to diagnose active or latent infections. As the virus is so prevalent, serology assays remain the assays of choice to accurately diagnose active infections with a high level of sensitivity.
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What is a PCR test?

SARS Frequently Asked Questions
PCR (or polymerase chain reaction) is a laboratory method for detecting the genetic material of an infectious disease agent in specimens from patients. This type of testing has become an essential tool for detecting infectious disease agents.
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The Hepatitis Council of NSW - FAQ
PCR tests detect or measure the actual hepatitis C virus in a sample of blood. They can tell if someone has hepatitis C virus or just has antibodies from a past infection. There are three types of PCR test - viral detection, viral load and viral genotype. Each test provides different information about a person's hepatitis C infection. PCR stands for polymerase chain reaction.
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Can I transmit MCF to healthy bison by handling MCF affected bison, their discharges or tissues?

Malignant Catarrhal Fever, Frequently Asked Questions on Bis...
MCF virus is transmitted by sheep in most instances. There is no documented evidence of person-to-bison transmission. Normal veterinary infection control precautions should be followed when caring for a bison suspected to have this viral infection.
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What does a positive result from RT-PCR mumps test from clinical material mean?

NIP: Diseases/Mumps/Mumps Lab Testing Q&As
A positive RT-PCR signal indicates the presence of mumps viral RNA. The positive result should be used only to support a clinical diagnosis of mumps since persons recently immunized against mumps may have limited viral shedding following vaccination.
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Can I be antibody positive and healthy?

Asian Pacific AIDS Intervention Team
YES. It is possible for individuals to be antibody positive and healthy. For every three cases of AIDS, it is estimated there are ten cases of HIV-related symptoms, and many more cases of persons who are antibody positive without symptoms.
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Why should I use serology/immunological tests instead of PCR?

Kaposi's Sarcoma,HHV 8 testing,Frequently Asked Questions
HHV-8 DNA can be detected in peripheral blood cells from only about half of infected persons with the use of standard PCR assays Since PCR detection systems appear to exhibit low sensitivity when DNA from peripheral blood cells is used as a template, serological assays have been proven more useful for epidemiology studies and diagnosis of HHV-8 infection, particularly for detecting previous exposure to the virus.
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What do I do if I test positive?

FAQ
Follow through with your medical providers instructions including taking all medicine and abstaining from sex for the specified amount of time. It is also very important that your sex and/or needle sharing partners are informed of the contact and receive testing and any treatment that are needed.
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New Page 1
It is of the utmost importance to your life that you seek out a doctor qualified to treat this disease. Your doctor will guide you to counseling, support groups and assistance services specifically for people that are HIV positive. You should also discuss the necessary changes to your life-style so as to not further endanger yourself and others. Your life is not over. You can live a longer, more fruitful life if you seek and receive treatment early in the disease process.
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What is a positive test?

Tilt Table Test: Frequently Asked Questions
A tilt table test is called positive if a patient develops a drop in blood pressure associated with symptoms. The symptoms that patients experience are varied and have included lightheadedness, nausea, a cold and clammy feeling, sweating, a "spacey" feeling, or a feeling like you are about to black out. Rarely, blood pressure falls without the patient developing symptoms. In these cases, we try to continue the test until the patient develops symptoms.
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What if I test positive for an illegal substance?

Frequently Asked Questions
Testing positive for drug use is a violation of conditions of release and as such, a violation would be submitted to the Court which could result in revocation of release.
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What if I test HIV positive?

American Social Health Association - Learn about STDs/STIs
There are many things you can do to help protect your health if you test positive for HIV. Seeking health care early and maintaining a healthy lifestyle can help a person stay healthy. Some specific things you can do if you're positive for HIV are: See a doctor, even if you feel well. If possible, see a doctor who is familiar with treating people with HIV. Health care providers can inform you on what tests and drug treatment are right for you.
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What if I test positive for HIV?

HIV Frequently Asked Questions - Southern Nevada Health Dist...
If you test positive for HIV, the sooner you take steps to protect your health, the better. Early medical treatment and a healthy lifestyle can help you stay well. Prompt medical care may delay the onset of AIDS and prevent some life-threatening conditions. The Health District Office of AIDS offers an Adult Evaluation Clinic at the Ravenholt Public Health Center.
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How long can bison be infected with MCFV before clinical signs develop?

Otoole MCF
Our limited knowledge on this subject suggests that bison may be infected for extended periods, in some instances years, before developing MCF. More work is needed on this aspect of the disease. A recent study performed by a veterinary epidemiologist in Canada, Dr. John Berezowski at WCVM in Saskatoon, demonstrated that bison develop clinical signs as soon as 52 days and as late as 8 months after exposure to infected sheep.
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Can I test positive for HIV and still look and feel healthy?

AIDS Project New Haven FAQ
Even if you look and feel healthy, people who have HIV can spread the virus to others through sharing needles and syringes or having sex without a latex barrier.
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What is coronavirus serology (the 'FIP test')?

The Cat Group: FIP (Feline Infectious Peritonitis) FAQs
Coronavirus serology is a laboratory test that detects antibodies in a cat,s blood sample against feline coronavirus (FCoV). However, this blood test does not have the ability to distinguish between different strains of FCoV, and cannot differentiate between strains that cause FIP and those more common strains that do not.
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If the test band is faint, is the pregnancy test positive?

Early Pregnancy Tests and Ovulation Predictor Kits: FAQ
A positive result will always be indicated by the presence of a distinct color band in the 'test' region of the pregnancy test strip or midstream test (accompanied by the presence of the 'control' band). If the test is faint (in comparison to the control band), the test may be positive, though the presence of hCG in the woman's body - or urine sample - may be low. The presence of hCG doubles every two days in a pregnant woman.
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What test should I use to confirm a diagnosis on a live bison with clinical signs suggestive of MCF?

Malignant Catarrhal Fever, Frequently Asked Questions on Bis...
The best one to use for diagnosing active disease is the PCR test. Blood collected into an EDTA-anticoagulant tube (purple-top tube) is the best sample to obtain from live animals. Both the PCR test and a newly developed serological test can be run on one purple-top blood sample. The carcass of an animal that dies of MCF-like signs should be examined post-mortem by your veterinarian or better still a pathologist at a veterinary diagnostic laboratory.
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What proportion of MCFV-seropositive bison subsequently develop clinical signs of MCF?

Otoole MCF
We are doing a study to establish this. It clearly happens, but the percentage is low. No precise figures are available yet. Many factors are likely to affect the probability that a subclinically affected bison will develop clinical disease. One of the most important of these is stress.
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What happens if I get a negative ECM or PCR test result?

FREQUENTLY ASKED QUESTIONS:
A woman who has a negative ECM (enriched culture medium) or PCR (polymerase chain reaction) test result at 35 plus weeks of pregnancy does NOT need to be offered intravenous antibiotics in labour to prevent GBS infection in her baby (but antibiotics may be indicated for other reasons) .
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Can you get a false positive hepatitis C test result?

AIDS Action Committee of Massachusetts:
It is possible to get a false positive test result. This happens when a doctor or laboratory has not performed a confirmatory antibody test before giving people their results. When a person has an antibody test, the lab usually runs two different kinds of tests. One is called an EIA test which is highly sensitive. It can sometimes overreact, so a positive result with the EIA is usually followed up with a RIBA test which is a sophisticated, highly-specific, antibody test.
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When I get a positive on an ovulation test, when is the best time to have intercourse?

Early Pregnancy Tests and Ovulation Predictor Kits: FAQ
To increase the chance of conception, it is best to have intercourse the day of the LH surge as well as following three days after. A faint line (or a faint positive test band) does not indicate a positive result for an LH surge. While the presence of a faint line on a pregnancy test may indicate a positive result, a faint line on an OPK is always negative. Please refer to the images on our instruction pages to interpret results.
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What if my test result is positive?

HIV/AIDS Program
A positive result means antibodies to HIV were found in your body. Prompt medical care may delay the onset of AIDS and prevent some life-threatening conditions. Make sure that your counselor sets up a medical appointment for you before you leave his/her office. The counselor may also set up an appointment with an agency providing case management to persons infected with HIV/AIDS.
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What if my HBsAg test is positive?

Hepatitis B: ACIP 2005 | CDC Viral Hepatitis
You should receive medical follow-up, including counseling and evaluation for chronic liver disease and the need for antiviral treatment. Any susceptible contacts should also be identified, tested for chronic infection, and vaccinated appropriately.
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What do I do if my partner has a positive test?

FAQ
You need to schedule an appointment for testing and treatment as soon as possible. It is very important that you mention to your medical provider that you have been in contact with an STD. Do not have sex until both you and your partner have completed your treatment.
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What about "all-natural" supplements; can they cause a positive test?

USATF - Anti-Doping - Frequently Asked Questions
Yes. Some substance that are banned are also derived from plants and are therefore consider natural. There is no guarantee that there are not ingredients in the product that are not listed on the package. It is important to remember that the use of ALL nutritional products is completely at your own risk. This information is intended to be a general overview of drug testing issues. Please obtain all the original documents and information regarding drug testing and read them thoroughly.
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