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What policies govern use of stem cell lines from WiCell Research Institute?

FAQs [Stem Cell Information]
WiCell has published FAQs About WiCell's Policies on the Use of Its hESC Lines (136k PDF file; get Adobe Reader) to address this question.
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Why do scientists want to use stem cell lines?

FAQs [Stem Cell Information]
Once a stem cell line is established from a cell in the body, it is essentially immortal, no matter how it was derived. That is, the researcher using the line will not have to go through the rigorous procedure necessary to isolate stem cells again. Once established, a cell line can be grown in the laboratory indefinitely and cells may be frozen for storage or distribution to other researchers.
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Why not use adult stem cells for research and stay away from the whole embryonic stem cell issue?

Graduate School of Biomedical Sciences | Stem Cell Research ...
Although there are many ethical and scientific issues with embryonic stem cells, these cells have the greatest capacity to make new tissues. To date, adult stem cells have not been shown to give rise to the variety of tissues that embryonic stem cells potentially can. Additionally, under certain conditions, embryonic stem cells can form cancerous cells. For this reason, embryonic stem cells have the potential to be studied as a model of cancer development.
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What is stem cell research?

Genomics|Frequently Asked Questions
Stem cell research is a hot topic in science and the media. Stem cells renew themselves for long periods of time through cell division. When a stem cell divides, it can either remain a stem cell or become another type of cell with a more specialized function such as a blood cell, a muscle cell, or a brain cell. Scientists are investigating using cell- based therapies to treat diseases. To find out more about stem cell research, visit the National Institutes of Health website.
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I proposing human subjects research if my studies will use ONLY cell lines?

FAQs - FAQs about Research Using Human Specimens, Cell Lines...
Research that proposes the use of human cell lines available from the American Type Culture Collection or a similar repository is not considered human subjects research because the cells are publicly available and all of the information known about the cell lines (perhaps, including the donor) is also publicly available.
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Why is cloning associated with stem cell research? What is the difference?

Graduate School of Biomedical Sciences | Stem Cell Research ...
times it is assumed that stem cell research is exclusively cloning. This is a misconception since stem cell research covers a wide range of topics – partly described in this FAQ section. At times it is difficult to separate stem cell research from cloning, since the latter might generate embryonic stem cells. To reiterate, the majority of stem cell research is exclusive of cloning.
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Is embryonic stem cell research going on now?

Graduate School of Biomedical Sciences | Stem Cell Research ...
With respect to federal funding for research, only the embryonic stem cell lines approved for research by President Bush in 2001 may be used. Detailed information on these cells can be found at: http://escr.nih.gov. Several laboratories around the country also conduct embryonic stem cell research using private funding. This research is monitored by an Institutional Review Board (IRB) within a privately funded institution.
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What kinds of stem-cell research will be supported?

NYAMR: FAQ
There are two fundamental types of stem cells. Embryonic stem cells have the potential to generate all the different tissues of the body. Tissue-specific stem cells generate the cell types found in a single tissue, such as the brain or the pancreas. This bill will support research on both types of cells, as well as on other aspects of stem-cell medicine. It is targeted at all types of stem-cell research that offer therapeutic potential, including tissue-specific stem-cell research (ie.
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Will stem-cell research help people with PXE?

PXE International - Eye Treatments and Procedures
Stem-cell research is an area of science that can assist in understanding how cells in the body develop, and that may help to find ways to reliably grow tissues that can be used for transplants. Stem cells may also help develop other treatments for disorders and conditions, and experiments are already under way to test treatments for vision loss using tissues developed with the help of stem cells.
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When does NIH anticipate that more stem cell lines will become available?

FAQs [Stem Cell Information]
of March 2007, there are 21 independent, fully developed stem cell lines available for widespread distribution to researchers. Providers of these 21 cell lines all received an NIH Infrastructure award. This number compares to 17 in 2004 and 1 in April 2002. The increased availability of the lines is a direct consequence of NIH's funding of Infrastructure awards to support cell providers to develop their eligible lines into distribution-quality, well-characterized cell lines.
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Why not do this research with non-embryonic stem cell lines?

CellNEWS
Non-embryonic stem cell lines involve cells that are more differentiated and less capable of being programmed into various cell lines. Simply put, as the cell line ages it loses its capability to differentiate itself into various tissues and thus is less useful.
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What are stem cells and what stem cell research is being done in diabetes?

Stem cells are immature cells that can replicate themselves and can develop into different kinds of cells as they mature. For instance, pancreatic islet cells can develop from cells that can also become liver cells. Some investigators claim to have found cells in the bone marrow that can develop into islet cells. Stem cell research is very controversial, because of the concern that single cells or small groups of cells could theoretically be used to create human beings.
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Why is stem cell research so important?

Frequently Asked Questions | The Harvard Stem Cell Institute
Stem cells are the source of all tissues of the body, and understanding their properties is fundamental to our understanding of human biology in health and disease. In particular, stem cells offer the possibility of a renewable source of replacement cells to treat a wide variety of diseases and disabilities, including diabetes, neurological disease, cardiovascular disease, blood disease and many other conditions.
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Where can I get information on stem cell research?

FDA/CBER - Consumer FAQs about Tissue
Stem cells can be found throughout the body. There are stem cells in tissues and organs as well as in umbilical cord blood and peripheral blood (i.e., hematopoietic stem cells). At this time there is no licensed stem cell treatment. If you are interested in clinical trials using stem cell therapies, you may want to visit www.clinicaltrials.gov. This site provides regularly updated information about federally and privately supported clinical research in human volunteers. ClinicalTrials.
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What are the types of stem cell research?

jwsoccergurly's Xanga Site
There are four types of cell therapy, early embryonic stem cells, fetal stem cells, umbilical cord blood stem cells, and adult stem cells. The early embryonic stem cells are stem cells that are derived from fertilized embryos less than a week old and are totipotent meaning that they can replace just about any type of cell in the body.
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What is a stem cell?

Graduate School of Biomedical Sciences | Stem Cell Research ...
A stem cell is an uncommitted cell that has the potential to develop into cells of a specific tissue (such as the hematopoietic stem cell developing into all of the blood cells). Within the fetus and the adult, stem cells are found in various areas of the body. Embryonic stem cells are the precursors to all stem cells as well as all other tissues of the body.
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Why create a Stem Cell Institute at Harvard?

Frequently Asked Questions | The Harvard Stem Cell Institute
Stem cells represent an extraordinary opportunity and challenge that involves areas of expertise not encompassed in any one discipline, department or school. For example, basic biology must interface with medical expertise if the promise of this field is to be fully realized. At the same time, clinical and laboratory scientists must engage with those attuned to the political, societal and ethical implications of the research.
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How many human embryonic stem cell lines are there?

ISSCR :: Stem Cell Science : Frequently Asked Questions
The available number of human embryonic stem cell lines is a matter of some debate. To date, over 100 human embryonic stem cell lines have been derived worldwide. However, most of those lines are not adequately characterized yet. And only 22 cell lines are eligible for federal funding in the USA. Detailed information on those 22 cell lines can be found at the National Institutes of Health Human Stem Cell Registry at http://stemcells.nih.gov.
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Michigan Citizens for Stem Cell Research & Cures
Once a stem cell line is established, essentially, it can grow forever according to the National Institutes of Health (NIH). That is, the researcher using the line will not have to go through the rigorous procedure necessary to isolate stem cells again. Once established, a cell line can be grown in the laboratory apparently indefinitely and cells may be frozen for storage or distribution to other researchers.
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Common Medical and Disability Questions and Answers
Once a stem cell line is established from a cell in the body, it is essentially immortal, no matter how it was derived. That is, the researcher using the line will not have to go through the rigorous procedure necessary to isolate stem cells again. Once established, a cell line can be grown in the laboratory indefinitely and cells may be frozen for storage or distribution to other researchers.
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Are all of the cell lines on the NIH Human Embryonic Stem Cell Registry de-identified?

UCSF Stem Cell Research - Frequently Asked Questions
Yes. However, because of California law, CHR review (usually Expedited review) is still required for research using registry cell lines. Donors may be recontacted if, in the donation consent form, they have agreed to be recontacted. If researchers expect they may want to recontact donors, the initial consent form should describe the circumstances and purposes of recontact.
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Why is there so much controversy surrounding embryonic stem cell research?

Frequently Asked Questions | The Harvard Stem Cell Institute
present, the only known way to derive embryonic stem cells involves the destruction of a blastocyst-stage embryo. Some people are opposed to this research because they consider the blastocyst to be morally equivalent to a human individual.
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Why is it important for Wisconsin to be out in front when it comes to stem cell research?

Frequently Asked Questions
Wisconsin is already recognized as a worldwide leader in human embryonic stem cell research, but other states-and nations-are eager for a bigger piece of the pie. Singapore, the U.K., California, Connecticut, Massachusetts and New Jersey are spending millions of dollars to build new labs, fund research projects and attract top scientific talent.
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What are the economic implications of stem cell research?

Frequently Asked Questions
Like other forms of biotechnology, technology that emanates from research on embryonic stem cells has the potential to fuel Wisconsin's economy. Companies founded on stem cell research are already beginning to emerge here.
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Is there oversight of stem cell research at UCLA?

ISCBM FAQ
Yes. There are several committees that oversee stem cell research at UCLA. The UCLA Institutional Review Board (IRB) www.oprs.ucla.edu is required by California law to review all stem cell research with human subjects. The IRBs are composed of faculty, community representatives and consultants representing special subject populations.
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What is the government? perspective on stem-cell research?

jwsoccergurly's Xanga Site
According to the Stem Cell Therapeutic and Research Act of 2005 (H.R. 2520), the Administration supports the use of umbilical cord blood cells. These cells are taken from the placenta and umbilical cord after birth. This harms neither the mother nor the child. The government also supports the further use of stem cell lines. Stem cell lines are created from embryos that have already been destroyed and are able to regenerate indefinitely.
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What is the Catholic Church? teaching on stem cell research?

jwsoccergurly's Xanga Site
The Catholic Church is not opposed to stem cell research at all. With the use of adult tissue, umbilical cord blood, and other sources, such as bone marrow, blood, muscle, fat, nerves, and even in the pulp of baby teeth, there are no moral issues. The Catholic Church encourages technological advances and medical development however, what it calls for is reflected on the use of human embryos for stem-cell research and if it is moral and ethical or not.
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How far along is stem cell research?

StemLifeLine : FAQ
Stem cells have been used for the past 30 years for treatment in patients. However, so far the stem cells most commonly used in therapy are adult stem cells derived from the bone marrow which have limited applicability and growth potential. There are many therapeutic applications currently in research that show very encouraging results.
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