In 1886, Kobner introduced the name epidermolysis bullosa hereditaria to describe a multigeneration affected family with mildly generalized, predominantly acral, serous blistering. This name is still widely used today. During the end of the nineteenth and beginning of the twentieth centuries, other famous dermatologists, including Brocq and Hallopeau, continued to group these patients under such terms as congenital traumatic pemphigus, congenital traumatic blistering, or acantholysis bullosa.

Epidermolysis Bullosa, or EB for short, is the name given to a group of rare genetic blistering skin disorders. EB causes the skin to be so fragile that even minor rubbing can cause blistering. In severe EB, daily bandage changing is required to treat the many open wounds and blisters. EB can also effect other areas such as the eyes and internally such as the mouth, esophagus, stomach, intestines, upper airway, bladder, and genitals. The skin is made up of many layers. See similar questions...

Of these, less than 300 have the same form of EB that I was born with. (Recessive Dystrophic - Hallopeau Siemens Epidermolysis Bullosa.) Only one in a million babies are born with the Recessive Dystrophic form of EB (RDEB). I prefer to say I'm one in a million  :o) See similar questions...

Most people with EB have inherited the condition through genes they have received from one or both parents. The faulty genes cause structural abnormalities in the skin. Genes govern the formation of different types of protein in the skin, including collagen and keratin. When any of these proteins is bad, the skin becomes so fragile it can literally fall apart. See similar questions...

Some forms of EB are dominant, some are recessive and some are spontaneous mutations (abnormal changes in a gene that occurred during the formation of the egg or sperm) In dominant forms of EB, the disease gene is inherited from only one parent who has the disease and there is a 50% chance with each pregnancy the baby will have EB. In the recessive forms, the disease gene is inherited from both parents. Neither parent shows signs of the disease, they are just carriers of the EB gene. See similar questions...

By doing a skin biopsy (taking a small sample of skin and examining it under a microscope), a dermatologist can identify where the skin separation occurs and what form of EB the person has. One diagnostic test involves use of a microscope and reflected light to see if proteins needed for forming connecting fibrals, filaments or hemidesmosomes are missing or reduced in number. See similar questions...

There is currently no cure for EB. At this time the best hope is gene therapy. In 1993 the gene that causes Dystrophic EB was located. That was the first major step. More advances are being made every year giving much hope for the future. Scientists are currently testing the delivery of modified cells to genetically altered mice that have EB traits. See similar questions...

There are currently only two types of EB that are considered lethal. The first is Junctional Herlitz, which is often deadly to newborns. Junctional Herlitz effects internally, including the airway and other internal organs causing major complications. Many with this form pass away within a few weeks of birth.  The other form is RDEB-HS (the kind I have). See similar questions...

Thankyou for taking the time to learn about Epidermolysis Bullosa. Please help spread awareness and pass this site onto others. No, not at all, in fact most with EB excel in school. EB children can be mainstreamed into regular classes with the other kids. Some severe forms of EB cause the person/child to look much younger than they actually are, however don't let this fool you! In some forms of EB the skin does get better with age, in some cases dramatically better. See similar questions...

Most experts agree that acupuncture is over 3000 years old. Oriental Medicine is the most widely utilized healing system on the planet. Its roots are in China, but evidence of its potential to help the sick and injured are apparent in many places, including all of Asia, Europe and North and South America. See similar questions...

The effects of red light on cellular function have been known since 1880 however the clinical benefits were only discovered by accident during laser safety tests in 1967. The first low-power lasers suitable for treating pain became available commercially in the late 1970's and ever since then, laser therapy has been widely utilized in Europe by physical therapists, nurses and doctors. Now, after FDA approval in 2001, laser therapy is quickly gaining popularity in the USA. Yes. See similar questions...

Annual filing of your Health History is legally mandatory under the standards of the College of Massage Therapists, and it provides an avenue for your therapist to explore any issues that might influence your treatment. Ultimately, it is for your safety that we need to be informed of your history. It allows your RMT to be informed and equipped to treat you safely and effectively. See similar questions...

In zsh, you need to set three variables to make sure your history is written out when the shell exits. For example, HISTSIZE=200 HISTFILE=~/.zsh_history SAVEHIST=200 $HISTSIZE tells the shell how many lines to keep internally, $HISTFILE tells it where to write the history, and $SAVEHIST, the easiest one to forget, tells it how many to write out. The simplest possibility is to set it to the same as $HISTSIZE as above. There are also various options affecting history; see the manual. See similar questions...

When a reporter or author writes a story, article or book, he/she will investigate the material. He will interview people, record what her sees and may report on previous written information found in books, journals, letters. Interviewing people create a live report of the story. It is an "oral" report of an event. An oral history is the same thing. It is the documenting of history through what people remember and tell to a reporter/recorder. See similar questions...

SpamCop is the premier web-based service for reporting and blocking spam, founded in 1998 by Julian Haight. SpamCop processes over one million spam complaints a day and is supported by hundreds of thousands of users, a knowledgeable volunteer community, and a professional staff. SpamCop streamlines the process of determining the origin of spam emails and reporting them to the relevant Internet service providers. SpamCop offers both free and premium reporting services. See similar questions...

If you are going to trust them with your valuable data, don't deal with unnamed individuals hiding behind an anonymous web site. Use a company that has an established name and has been in the business for a number of years. DRS have been in IT business for more than two decades, specializing in data recovery for the past 9 years. See similar questions...