Yes. Prior to use, AVONEX in a prefilled syringe must be stored in a 2º-8ºC (36º-46ºF) refrigerator. Powdered AVONEX is stable at room temperature for up to 30 days. DO NOT EXPOSE ANY FORM OF AVONEX TO HIGH TEMPERATURES. DO NOT FREEZE ANY FORM OF AVONEX.
AVONEX is an interferon therapy. Interferons are naturally occurring proteins and glycoproteins produced by cells in response to biological triggers. They are part of the body's natural defense system. In the case of multiple sclerosis (MS), the body's immune system attacks the myelin in the central nervous system. Interferon beta can help limit that assault on the brain and spinal cord, and help control damage to the nerve cells.
No formal drug interaction studies have been conducted with AVONEX. In the placebo-controlled study, corticosteroids or ACTH were administered for treatment of relapses in some patients concurrently receiving interferon beta-1a. In addition, some patients receiving interferon beta-1a were also treated with anti-depressant therapy and/or oral contraceptive therapy. No unexpected side effects were associated with the combined use of these therapies. You should discuss this with your physician.
Most people who take AVONEX have flu-like symptoms (fever, chills, sweating, muscle aches, and tiredness) early during the course of therapy. These symptoms may be a result of the body's natural reaction to interferon, the active ingredient in AVONEX. The flu-like symptoms usually go away within 24 hours after the injection, and tend to diminish with continued use. AVONEX can cause other side effects, and some of them can be serious.
You should not take AVONEX if you are pregnant or planning to become pregnant. The reproductive toxicity of AVONEX has not been studied in humans, and there are no adequate and well-controlled studies of interferons in pregnant women. If you become pregnant while taking AVONEX, you should stop using AVONEX immediately and call your doctor. For more information call the AVONEX Pregnancy Registry toll-free at 1-800-811-0104.
Whether you are just starting therapy or having issues with your current administration, you should feel free to discuss various options with your doctor to make your therapy more convenient or comfortable. While many AVONEX users opt for self-injection, some patients have their injections administered by trained professionals (physicians or nurses) or trained caregivers (friends, spouses, or other family members).
AVONEX has a low (5%) incidence of neutralizing antibodies. In the EVIDENCE study, the incidence of neutralizing antibodies was 12 times higher in the Rebif (Interferon beta-1a) treatment group than in the AVONEX treatment group. The clinical significance of neutralizing antibodies is unknown.
If you have concerns about the size of the needle, please discuss this with your healthcare provider.
Biogen Idec currently does not have an auto-injector available for use in the United States. We are working hard to develop an IM auto-injector to make taking AVONEX treatment even easier. You should consult your doctor before making any changes in your AVONEX treatment.
Nursery® Water - Frequently Asked Questions
Refrigeration of Nursery® Water is not required prior to or after opening. Always make sure to replace the cap after opening and put the unused portion aside on a kitchen counter. Never store the water near solvents (like cleaning supplies) or food with strong odors. Also, do not store Nursery® Water in direct sunlight.
MPD Online Resource
Interferons are substances made by cells. They act by enhancing the immune functions of lymphocytes against viruses and some tumor cells. The interferon used for treatment of CML is a synthetic alpha-interferon. There is no doubt that this agent has a powerful effect against CML tumor cells, but the mechanisms by which this takes place are unknown.
AgriPhage Frequently Asked Questions | OmniLytics
No, AgriPhage does not have to be refrigerated. We recommend storing AgriPhage in a cool, dark and dry location, such as a shed or warehouse. AgriPhage can be refrigerated if you have the facility, however it is not a requirement.
Frequently Asked Questions About Hepatitis C
Interferon is a genetically created protein that helps to clear the hepatitis C virus from the blood and liver. Interferon also fights the formation of scar tissue in the liver and reduces liver inflammation.
Yes. If Webber Naturals™ Acidophilus is not refrigerated, it looses about 3% potency per month. Phase 2™, the carb neutralizer ingredient was used in human studies and subjects were given standardized or recommended meal plans. The carbohydrates consumed per meal, were based on an average meal size, not twice as much as one person would consume at a meal. Doses taken above the manufactures label recommendation may cause intestinal discomfort, gas or loose stools.
Greens Plus - Superfood rich in chlorophyll.
GREENS+® contains living plant foods and probiotic cultures that break down when exposed to light, heat and oxygen. Once opened, shelf life is prolonged when stored in the refrigerator. Unopened, GREENS+® can be store at room temperature in a dry, cool place.
The time required for the solution in the prefilled syringe to warm to room temperature is dependent upon both the refrigeration temperature (which can range from 2º-8ºC or 36º-46ºF) and the ambient room temperature (which can vary widely from 15-30ºC or 59º-86ºF); however, 30 minutes should be sufficient in most situations, or hold the syringe in your hand for 5 minutes. Do not use accelerated warming methods, such as placing it under warm water or in a microwave or oven.
Yes. AVONEX in a prefilled syringe may be kept outside of a refrigerator at room temperature (77º F or 25º C) for up to 12 hours. AVONEX in the powder form may be kept outside a refrigerator for up to 30 days at room temperature (77º F or 25º C). It is important to protect AVONEX from extreme hot or freezing temperatures. Extreme hot, such as glove compartments in the summer, or freezing conditions such as an unheated car in the winter, may reduce the stability of the drug.