Melatonin's long-term safety has not been established. There are growing concerns about the possibility of damage to the retina of the eye associated with melatonin use. you work as a pilot, trucker, railroader, or in another occupation in which a lack of alertness on the job could endanger yourself or others Because of concerns about transmission of viruses through animal products, melatonin derived from cow pineal glands should not be taken. See similar questions...

Yes. Several thousand people have taken melatonin in carefully monitored clinical studies, some in daily doses of several thousand grams or more. Without exception, these studies have shown no toxic effects and leading experts in the field agree that melatonin is remarkably safe. See similar questions...

Based on available studies and clinical use, melatonin is generally regarded as safe in recommended doses for short-term use. Available trials report that overall adverse effects are not significantly more common with melatonin than placebo." (U.S. National Institutes of Health) In the most extensive clinical trial to date a high dose of 75 milligrams of melatonin per day was given to 1400 women in the Netherlands for up to four years with no ill effects." (Newsweek, 6 Nov. 1995, 60-63.) See similar questions...

Melatonin is a potent antioxidant. It has both water and fat soluble properties-making it one of the only known antioxidants in nature that can protect all parts of a cell. Since melatonin has the unique ability to navigate the barrier systems of the body, it can protect virtually every cell in the body. In this way, it serves as a powerful safeguard against cell damage associated with aging and disease. See similar questions...

A non-invasive saliva test can detect hormonal rhythm disturbances by measuring your melatonin levels. A morning, evening, and midnight saliva sample is all that is required. It's safe, convenient, and economical. See similar questions...

Yes, as opposed to over-the-counter sleeping remedies, which can be addictive and harmful. It is completely natural and gentle, and safe for everyday use. The additional benefits are that it gives the immune system a boost and can help to reduce the effects of aging! See similar questions...

Melatonin levels decrease with age and this deficit may play an important role in the high frequency of insomnia among elderly people. A disruption in the normal sleep-wake cycle caused by shift work, jet lag, stress, or other factors can also trigger abnormal levels. Low levels of melatonin have been linked to depression and many degenerative diseases, such as AIDS and cancer. Melatonin also has the potential to modify ovarian function. See similar questions...

Because scientific research has revealed its powerful anti-aging, anti-cancer, and sleep enhancing effects, melatonin has received a lot of media attention in recent years. As a result, the popularity of melatonin as a hormonal supplement has skyrocketed. What many people don't realize, however, is that too much melatonin can be just as detrimental to your health as too little. Abnormally high levels of melatonin are an underlying cause of Seasonal Affective Disorder (SAD), for example. See similar questions...

Acute: Minor. About eight out of 100 people taking 5 mg. melatonin or less per day to prevent jet lag feel sleepy in the daytime. Fewer than two out of 100 on this dose suffer a headache, feelings of fuzziness or giddiness, or nausea. In research studies using doses up to 300 mg. daily, the side effects occurring most frequently were diarrhea, abdominal pain and headaches. See similar questions...

Melatonin is sold as a dietary supplement, not as a drug, often in health food and other grocery stores and some drug stores. Because it is not labeled as a drug, Food and Drug Administration (FDA) regulations that apply to medications sold in the United States do not apply to melatonin. The FDA does not require manufacturers of melatonin to demonstrate that their product is safe and effective nor to monitor its safety and efficacy, as is the case for drugs. See similar questions...

As we age our bodies produce less and less melatonin so that by age 45, most people produce less than half the melatonin they produced at age 20. This reduction in melatonin can make restful sleep more difficult to achieve. Dietary supplementation with MELATONEX can help to restore the melatonin we need for restful, natural sleep.* See similar questions...

For your health and safety the melatonin in MELATONEX is produced in a laboratory, eliminating the risk of contamination associated with animal sources. See similar questions...

People who have the following conditions should always check with their physicians before taking melatonin: persons who are pregnant or lactating, or have an autoimmune, seizure or endocrine disorder. See similar questions...

Review #1 - ME/CFS Sufferer (inc. general info) : Melatonin review / Melatonin suggested use ~ "Melatonin is your natural 'sleep hormone' that your brain produces when it gets dark. PVFS/CFS/ME and FMS sufferers have been shown to have abnormal levels of melatonin. Research suggests that ME/CFS..." More... Review #1 - ME/CFS Sufferer: Chronic Fatigue Diet ~ "This book really woke me up to the importance of what you eat when you have CFS . A good CFS diet is crucial..." More. See similar questions...

Melatonin therapy has been shown effective in treating hormonal rhythm disturbances that aggravate symptoms of PMS, insomnia, fatigue, and mood disorders. Melatonin can be extremely effective in treating people whose internal rhythms have been temporarily thrown off by jet lag or changes in work shifts. Insomnia patients given oral doses of melatonin will often show a marked improvement in their sleep patterns. See similar questions...

If you answered yes to any of these questions, you may be suffering from hormonal imbalance. Ask your Health Care Provider if an Adrenocortex Stress Profile from Genova Diagnostics might be helpful for you. See similar questions...

The secretion of melatonin follows a daily rhythm governed by the body's master clock. This clock is located in the brain and is synchronized by regular exposure to the 24-hour cycle of darkness and light. Melatonin secretion may serve as a biological time cue. Although its natural secretion in the body peaks at night, melatonin does not control sleep. If it did, night workers would not be able to sleep in the daytime when melatonin levels are low. See similar questions...