In some cases, cleft lips and palates can be detected from routine ultrasounds of the baby in the mother's womb. When this happens, we encourage the parents to come in and see us so we can discuss potential treatment for the baby. However, many cleft lips and palates are not detected until birth.

A cleft lip is an opening in the lip. A cleft palate is an opening in the roof of the mouth. Clefts result from incomplete development of the lip or palate while the baby is forming before birth. Babies’ lips and palates develop separately during the first three months of pregnancy. In most cases, the left and right parts of the lip come together, or “fuse,” creating the two vertical lines on the normal upper lip. See similar questions...

We are studying cleft lip and palate because it is a common birth defect with a significant health care burden. Children require multiple surgeries to correct the lip, palate, and nose. The causes of cleft lip and palate are not known but genes and environmental factors are considered to be important. Identification of the causes may allow development of new treatments and/or identification of individuals who are at risk to have children with cleft lip and palate. See similar questions...

The purpose of this research study is to identify the genes and environmental factors causing isolated cleft lip and palate. We are collecting information about pregnancy specific exposures and obtaining blood samples from which DNA (genetic material) will be made. We will use the DNA to determine whether specific genes are associated with cleft lip and palate. We will also correlate whether specific types of exposures are linked to cleft lip and palate. See similar questions...

About one in 1,000 babies are born with cleft lip and/or palate. This is the fourth most common birth abnormality. See similar questions...

In the early weeks of development, long before a child is born, the right and left sides of the lip and the roof of the mouth normally grow together. Occasionally, however, in about one of every 800 babies, those sections don't quite meet. A child born with a separation in the upper lip is said to have a cleft lip. A similar birth defect in the roof of the mouth, or palate, is called a cleft palate. See similar questions...

The American Cleft Palate-Craniofacial Association recommends that children with clefts be seen by an team of doctors and care providers to best plan care and treatment. Speech pathologist - evaluates and treats speech, language, voice, swallowing, fluency, and other related disorders. The first clinic visit usually happens in the first year, but not necessarily before surgery. See similar questions...

In most cases, these babies are unable to breastfeed. This is because they do not have a separation between the nose and mouth, so they cannot create enough pressure to suck effectively from the breast. They usually feed successfully with bottles and teats specifically designed for babies with clefts. See similar questions...

You will have a follow-up appointment with the Plastic Surgeon between 6-12 weeks post surgery, depending on the surgeon's request. This will take place in the Cleft Palate Clinic or in the private rooms. See similar questions...

Individuals born with cleft lip and palate, their parents, and other family members. We are particularly interested in families in which there is more than one family member with cleft lip and palate. See similar questions...

Permission to contact additional relatives may also be requested especially if there is a family history of cleft lip and palate. All information is kept strictly confidential. Participation is voluntary and you can withdraw from the study at any time. This study has been approved by the Institutional Review Board of the University of Texas Health and Science Center - Houston. No. The questionnaire can be completed by telephone or mail, and the blood samples can be sent by mail. See similar questions...

To learn more about the cleft lip and palate study and how to take part in the search for the causes of cleft lip and palate, please contact: See similar questions...

It is estimated that there are 250,000 children and adults alike waiting for cleft lip or palate repair. See similar questions...

A cleft palate is a hole in the roof of the mouth (the palate) that can involve the hard palate and/or the soft palate. It can be unilateral (one sided) or bilateral (two sided). It occurs during the first trimester of pregnancy when parts of the palate fail to completely fuse. See similar questions...

Generally the repair of the cleft lip occurs between 3-6 months of age, and the repair of the cleft palate occurs between 6-9 months. This can vary depending on the child's cleft and the general health of the child. See similar questions...

interdisciplinary team means that the children we treat benefit from expertise that spans numerous disciplines in cleft lip and palate care. With our surgeons, orthodontists, language pathologists, dentists, geneticists, psychologists, and nurses, we can provide comprehensive, coordinated care that addresses all of the aspects of craniofacial treatment. See similar questions...